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  4. Sialyl Lewis A sodium

Sialyl Lewis A sodium (SLeA sodium) is a carbohydrate-type antigen that can serve as a tumor marker, with upregulation observed in various tumor cells such as cervical cancer, human pancreatic cancer, and colon cancer cells. Sialyl Lewis A sodium is involved in the migration and adhesion of tumor cells. Additionally, elevated expression of Sialyl Lewis A sodium may also lead to pregnancy abnormalities.

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Sialyl Lewis A sodium

Sialyl Lewis A sodium Chemical Structure

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Sialyl Lewis A sodium Related Antibodies

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Description

Sialyl Lewis A sodium (SLeA sodium) is a carbohydrate-type antigen that can serve as a tumor marker, with upregulation observed in various tumor cells such as cervical cancer, human pancreatic cancer, and colon cancer cells. Sialyl Lewis A sodium is involved in the migration and adhesion of tumor cells. Additionally, elevated expression of Sialyl Lewis A sodium may also lead to pregnancy abnormalities[1][2][3].

Molecular Weight

842.73

Formula

C31H51N2NaO23
Appearance

Solid

SMILES

O=C(O[Na])[C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)O[C@@H]2[C@H]([C@@H](O[C@@H]([C@@H]2O)CO)O[C@H]([C@H](C=O)NC(C)=O)[C@@H]([C@H](O)CO)O[C@H]3[C@H]([C@@H]([C@@H]([C@@H](O3)C)O)O)O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 125 mg/mL (148.33 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1866 mL 5.9331 mL 11.8662 mL
5 mM 0.2373 mL 1.1866 mL 2.3732 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.1866 mL 5.9331 mL 11.8662 mL 29.6655 mL
5 mM 0.2373 mL 1.1866 mL 2.3732 mL 5.9331 mL
10 mM 0.1187 mL 0.5933 mL 1.1866 mL 2.9665 mL
15 mM 0.0791 mL 0.3955 mL 0.7911 mL 1.9777 mL
20 mM 0.0593 mL 0.2967 mL 0.5933 mL 1.4833 mL
25 mM 0.0475 mL 0.2373 mL 0.4746 mL 1.1866 mL
30 mM 0.0396 mL 0.1978 mL 0.3955 mL 0.9888 mL
40 mM 0.0297 mL 0.1483 mL 0.2967 mL 0.7416 mL
50 mM 0.0237 mL 0.1187 mL 0.2373 mL 0.5933 mL
60 mM 0.0198 mL 0.0989 mL 0.1978 mL 0.4944 mL
80 mM 0.0148 mL 0.0742 mL 0.1483 mL 0.3708 mL
100 mM 0.0119 mL 0.0593 mL 0.1187 mL 0.2967 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Sialyl Lewis A sodium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sialyl Lewis ASLeABiochemical Assay ReagentsTumor markerInhibitorinhibitorinhibit

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