83512-85-0
83512-85-0
Chemical Structure
Carboxymethyl chitosan
- CAS No.: 83512-85-0
- Formula:N/A
- Molecular Weight:N/A
SMILES: [Carboxymethyl chitosan]
Biological Activity: Carboxymethyl chitosan is a derivative of chitosan. Carboxymethyl chitosan inhibits Apoptosis and ROS. Carboxymethyl chitosan increases the expression of Bcl-2 and reduces the expression of Bax, cytochrome c and caspase-3. Carboxymethyl chitosan inhibits the migration of various cells. Carboxymethyl chitosan exerts antitumor effects on Lewis tumors and hepatocarcinoma[1][2][3][4][5][6][7][8].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Carboxymethyl chitosan | 90% | Carboxymethyl chitosan is a derivative of chitosan. Carboxymethyl chitosan inhibits Apoptosis and ROS. Carboxymethyl chitosan increases the expression of Bcl-2 and reduces the expression of Bax, cytochrome c and caspase-3. Carboxymethyl chitosan inhibits the migration of various cells. Carboxymethyl chitosan exerts antitumor effects on Lewis tumors and hepatocarcinoma. | ||||||||||||||||||||
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References
- [1]. Chen XG, et al. The effect of carboxymethyl-chitosan on proliferation and collagen secretion of normal and keloid skin fibroblasts. Biomaterials. 2002 Dec;23(23):4609-14. [Content Brief]
- [2]. Kruczkowska W, et al. Medical Applications and Cellular Mechanisms of Action of Carboxymethyl Chitosan Hydrogels. Molecules. 2024 Sep 13;29(18):4360. [Content Brief]
- [3]. He B, et al. Carboxymethylated chitosan protects Schwann cells against hydrogen peroxide-induced apoptosis by inhibiting oxidative stress and mitochondria dependent pathway. Eur J Pharmacol. 2018 Apr 15;825:48-56. [Content Brief]
- [4]. Jiang Z, et al. Carboxymethyl chitosan represses tumor angiogenesis in vitro and in vivo. Carbohydr Polym. 2015 Sep 20;129:1-8. [Content Brief]
- [5]. Chen Q, et al. Carboxymethyl-chitosan protects rabbit chondrocytes from interleukin-1beta-induced apoptosis. Eur J Pharmacol. 2006 Jul 10;541(1-2):1-8. [Content Brief]
- [6]. Jiang Z, et al. Evaluation on biological compatibility of carboxymethyl chitosan as biomaterials for antitumor drug delivery. J Biomater Appl. 2017 Feb;31(7):985-994. [Content Brief]
- [7]. Jiang Z, et al. Preparation and anti-tumor metastasis of carboxymethyl chitosan. Carbohydr Polym. 2015 Jul 10;125:53-60. [Content Brief]
- [8]. Yang Z, et al. Acute toxicity of high dosage carboxymethyl chitosan and its effect on the blood parameters in rats. J Mater Sci Mater Med. 2012 Feb;23(2):457-62. [Content Brief]
