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Results for "

ME2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) Apoptosis (7) Autophagy (4) Biochemical Assay Reagents (6) DNA/RNA Synthesis (1) Endogenous Metabolite (4) HIF/HIF Prolyl-Hydroxylase (1) Histone Demethylase (5) Histone Methyltransferase (13) Isotope-Labeled Compounds (3) Microtubule/Tubulin (4) Nucleoside Antimetabolite/Analog (2) Oxytocin Receptor (3) PROTAC Linkers (1) Reactive Oxygen Species (4) Small Interfering RNA (siRNA) (1) Vasopressin Receptor (2)
By Research Areas:	Cancer (28) Cardiovascular Disease (1) Endocrinology (1) Infection (1) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (3)

By Targets:

Amino Acid Derivatives (1)

Apoptosis (7)

Autophagy (4)

Biochemical Assay Reagents (6)

DNA/RNA Synthesis (1)

Endogenous Metabolite (4)

HIF/HIF Prolyl-Hydroxylase (1)

Histone Demethylase (5)

Histone Methyltransferase (13)

Isotope-Labeled Compounds (3)

Microtubule/Tubulin (4)

Nucleoside Antimetabolite/Analog (2)

Oxytocin Receptor (3)

PROTAC Linkers (1)

Reactive Oxygen Species (4)

Small Interfering RNA (siRNA) (1)

Vasopressin Receptor (2)

By Research Areas:

Cancer (28)

Cardiovascular Disease (1)

Endocrinology (1)

Infection (1)

Inflammation/Immunology (1)

Metabolic Disease (1)

Neurological Disease (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12033

2-Methoxyestradiol 20+ Cited Publications 2-ME2; NSC-659853	Microtubule/Tubulin Reactive Oxygen Species Apoptosis Autophagy Endogenous Metabolite	Cancer
2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa ^[2] .

HY-12033S2

2-Methoxyestradiol-d5 2-ME2-d₅; NSC-659853-d₅	Isotope-Labeled Compounds Microtubule/Tubulin Reactive Oxygen Species Apoptosis Autophagy Endogenous Metabolite
2-Methoxyestradiol-d₅ is the deuterium labeled 2-Hydroxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6][7].

HY-15648

GSK-J1

5+ Cited Publications

Histone Demethylase Cancer

GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC₅₀ of 60 nM towards KDM6B.

GSK-J1 5+ Cited Publications	Histone Demethylase	Cancer
GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC₅₀ of 60 nM towards KDM6B.

HY-RS08271

ME2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ME2 Human Pre-designed siRNA Set A contains three designed siRNAs for ME2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ME2 Human Pre-designed siRNA Set A ME2 Human Pre-designed siRNA Set A

HY-15648D

GSK-J1 lithium salt

Histone Demethylase Cancer

GSK-J1 lithium salt is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC₅₀ of 60 nM towards KDM6B.

GSK-J1 lithium salt	Histone Demethylase	Cancer
GSK-J1 lithium salt is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC₅₀ of 60 nM towards KDM6B.

HY-12033S1

2-Methoxyestradiol-13C6 2-ME2-¹³C₆; NSC-659853-¹³C₆	Isotope-Labeled Compounds Microtubule/Tubulin Reactive Oxygen Species Apoptosis Autophagy Endogenous Metabolite	Cancer
2-Methoxyestradiol- ¹³C₆ is the ¹³C-labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].

HY-161313

DYB-03	Histone Methyltransferase HIF/HIF Prolyl-Hydroxylase	Cancer
DYB-03 is an oral active *HIF-1α/EZH2* inhibitor. DYB-03 inhibits migration, invasion, and angiogenesis of lung cancer cells and HUVECs in vitro and in vivo. DYB-03 induces apoptosis in 2-ME2 ^- and GSK126 ^-resistant of A549 and H460 cells .

HY-15648G

GSK-J1 sodium

Histone Demethylase Cancer

GSK-J1 sodium is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC₅₀ value of 60 nM towards KDM6B ^[2] .

GSK-J1 sodium	Histone Demethylase	Cancer
GSK-J1 sodium is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC₅₀ value of 60 nM towards KDM6B ^[2] .

HY-15648A

GSK-J2 2 Publications Verification	Others	Cancer
GSK-J2 is an isomer of GSK-J1 that does not have any specific activity. GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.

HY-15648I

GSK-J2 sodium	Others	Cancer
GSK-J2 sodium is the sodium form of GSK-J2 (HY-15648A). GSK-J2 is an isomer of GSK-J1, and does not have any specific activity. GSK-J1 (HY-15648) is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A .

HY-12033S

2-Methoxyestradiol-13C,d3	Microtubule/Tubulin Reactive Oxygen Species Apoptosis Autophagy Endogenous Metabolite	Cancer
2-Methoxyestradiol- ¹³C,d₃ is the ¹³C- and deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].

HY-15648F

GSK-J4 hydrochloride Maximum Cited Publications 36 Publications Verification	Histone Demethylase	Cancer
GSK-J4 hydrochloride is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A with IC₅₀s of 8.6 and 6.6 μM, respectively. GSK-J4 hydrochloride inhibits LPS-induced TNF-α production in human primary macrophages with an IC₅₀ of 9 μM. GSK-J4 hydrochloride is a cell permeable proagent of GSK-J1 ^[2] .

HY-15648B

GSK-J4 Maximum Cited Publications 36 Publications Verification	Histone Demethylase Apoptosis	Cancer
GSK-J4 is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A with IC₅₀s of 8.6 and 6.6 μM, respectively. GSK-J4 inhibits LPS-induced TNF-α production in human primary macrophages with an IC₅₀ of 9 μM. GSK J4 is a cell permeable proagent of GSK-J1 ^[2] . GSK-J4 induces endoplasmic reticulum stress-related apoptosis .

HY-138604

5'-O-DMT-N6-Me-2'-dA

DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Infection Cancer

5'-O-DMT-N6-Me-2'-dA is a nucleoside with protective and modification effects.
HY-66025

Fmoc-Lys(Me)2-OH hydrochloride

Amino Acid Derivatives Others

Fmoc-Lys(Me)2-OH HCl is a lysine derivative .

*5'-O-DMT-N6-Me-2'-dA*	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Infection Cancer
5'-O-DMT-N6-Me-2'-dA is a nucleoside with protective and modification effects.

*Fmoc-Lys(Me)2-OH hydrochloride*	Amino Acid Derivatives	Others
Fmoc-Lys(Me)2-OH HCl is a lysine derivative .

HY-163545

*Tc-Me2P*	Others	Cancer
Tc-Me2P is a 99MTC-labeled acrylamide (PnAO) derivative that contains two 4-methyl-2-nitroimidazole groups. The primary activity of Tc-Me2P is as an imaging agent for tumor hypoxia. By specifically binding to hypoxic regions in tumor tissue, it can be used for single photon emission computed tomography (SPECT) and positron emission tomography (PET) imaging to detect hypoxia in tumors. Tc-Me2P can be used to study the targeting of different chemical structures in tumors and normal tissues .

HY-P5006

*(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin* d(CH2)5[Tyr(ME)2, Dab5]AVP	Vasopressin Receptor	Cardiovascular Disease
(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin (d(CH2)5[Tyr(Me)2, Dab5]AVP) is a specific antagonist of vasopressin V_1a receptor, with a pA₂ of 6.71 .

HY-P4895

*(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin*	Oxytocin Receptor	Neurological Disease
(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin (OVT) is an oxytocin receptor antagonist. (d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin can be used for the research of neurological disease .

HY-154224

*2’-O-Me-2-thio-U-3’-phos phoramidite*	Nucleoside Antimetabolite/Analog	Cancer
2’-O-Me-2-thio-U-3’-phos phoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-P1162

*(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin* SKF 100273	Vasopressin Receptor	Metabolic Disease
(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin (SKF 100273) is a vasopressin V1 receptor selective antagonist .

HY-P2014

*(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin*	Oxytocin Receptor	Neurological Disease
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin is an oxytocin antagonist and can be used for the research of sexual behavior .

HY-P4397

*(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin*	Oxytocin Receptor	Endocrinology
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, an oxytocin receptor antagonist, abolishes oxytocin-enhanced inhibitory postsynaptic currents in CA1 pyramidal neurons .

HY-136964

Sulfo-NHS-Biotin sodium

Others Others

Sulfo-NHS-Biotin (sodium) stongly label single SDS-2ME soluble cuticular protein .

Sulfo-NHS-Biotin sodium	Others	Others
Sulfo-NHS-Biotin (sodium) stongly label single SDS-2ME soluble cuticular protein .

HY-100360

MS049	Histone Methyltransferase	Cancer
MS049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC₅₀s of 34 nM and 43 nM, respectively. MS049 reduces levels of Med12me2a and H3R2me2a in HEK293 cells. MS049 is not toxic and does not affect the growth of HEK293 cells .

HY-100360A

MS049 dihydrochloride	Histone Methyltransferase	Cancer
MS049 dihydrochloride is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC₅₀s of 34 nM and 43 nM, respectively. MS049 dihydrochloride reduces levels of Med12me2a and H3R2me2a in HEK293 cells. MS049 dihydrochloride is not toxic and does not affect the growth of HEK293 cells .

HY-W127629

MOBS	Biochemical Assay Reagents	Others
MOBS is an amphoteric buffer, a butane analogue of the Good buffers MOPS [3-(N-morpholino) propanesulfonic acid] and MES [2-(N-morpholino) ethanesulfonic acid] .

HY-128931

NH2-Ph-C4-acid-NH2-Me

PROTAC Linker 31
PROTAC Linkers Cancer

NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs .

NH2-Ph-C4-acid-NH2-Me PROTAC Linker 31	PROTAC Linkers	Cancer
NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs .

HY-13808

UNC 0631 2 Publications Verification	Histone Methyltransferase	Cancer
UNC 0631 is a potent histone methyltransferase G9a inhibitor with an IC₅₀ of 4 nM. UNC 0631 potently reduces *H3K9me2* levels in MDA-MB-231 cells with an IC₅₀ of 25 nM .

HY-D0858B

MES sodium salt 2-Morpholinoethanesulphonic acid sodium salt	Biochemical Assay Reagents	Others
MES (2-Morpholinoethanesulphonic acid) sodium salt is a buffering agent in biology and biochemistry. MES sodium salt is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES sodium salt is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments ^[2].

HY-D0858

MES 2-Morpholinoethanesulphonic acid	Biochemical Assay Reagents	Others
MES (2-Morpholinoethanesulphonic acid) is a buffering agent in biology and biochemistry. MES is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments ^[2].

HY-D0858A

MES monohydrate 2-Morpholinoethanesulphonic acid monohydrate	Biochemical Assay Reagents	Others
MES (2-Morpholinoethanesulphonic acid) monohydrate is a buffering agent in biology and biochemistry. MES monohydrate is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES monohydrate is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments ^[2].

HY-D0858E

MES potassium 2-Morpholinoethanesulphonic acid potassium	Biochemical Assay Reagents	Others
MES (2-Morpholinoethanesulphonic acid) potassium is a buffering agent in biology and biochemistry. MES potassium is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES potassium is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments ^[2].

HY-D0858C

MES hydrate 2-Morpholinoethanesulphonic acid hydrate	Biochemical Assay Reagents	Others
MES (2-Morpholinoethanesulphonic acid) hydrate is a buffering agent in biology and biochemistry. MES hydrate is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES hydrate is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments ^[2].

HY-D0858D

MES hemisodium 2-Morpholinoethanesulphonic acid hemisodium	Others	Others
MES (2-Morpholinoethanesulphonic acid) sodium is a buffering agent in biology and biochemistry. MES sodium is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES sodium is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments ^[2].

HY-128579

DW14800	Histone Methyltransferase	Cancer
DW14800 is a protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC₅₀ of 17 nM. DW14800 reduces H4R3me2s levels and enhances the transcription of HNF4α, but does not alter PRMT5 expression. Anti-cancer activity .

HY-D0858S

MES-13d	Isotope-Labeled Compounds	Others
MES-d₁₃ is the deuterium labeled MES[1]. MES (2-Morpholinoethanesulphonic acid) is a buffering agent in biology and biochemistry. MES is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments[2][3].

HY-152775

RK-701	Histone Methyltransferase	Cancer
RK-701 is an highly selective and non-genotoxic inhibitor of G9a with IC₅₀ value of 23-27 nM. RK-701 selectively up-regulates HbF, γ- Globin, BGLT3 expression, down-regulates H3K9me2 expression. RK-701 also has inhibition for BCL11A and ZBTB7A .

HY-156285

ZZM-1220	Histone Methyltransferase Apoptosis	Cancer
ZZM-1220 is a histone lysine methyltransferase G9a/GLP covalent inhibitor with IC₅₀s of of 458 nM and 924 nM, respectively. ZZM-1220 inhibits H3K9me2 in cells and significantly induces apoptosis of triple-negative breast cancer (TNBC) cells and blocks the cell cycle in the G2/M phase .

HY-157251

UNC8153 TFA	Histone Methyltransferase	Cancer
UNC8153 TFA is a potent and selective nuclear receptor-binding SET domain-containing 2 (NSD2)-targeted degrader with a K_d of 24 nM. UNC8153 TFA reduces the cellular levels of both NSD2 protein and the *H3K36me2* chromatin mark. UNC8153 TFA contains a simple warhead that confers proteasome-dependent degradation of NSD2 .

HY-13807

UNC0646 1 Publications Verification	Histone Methyltransferase	Cancer
UNC0646 is a potent and selective histone methyltransferase G9a inhibitor with an IC₅₀ of 6 nM. UNC0646 is also a potent GLP inhibitor (IC₅₀ <15 nM) and highly selective for G9a/GLP over SETD7, SUV39H2, SETD8 and PRMT3. UNC0646 reduces *H3K9me2* levels in MDA-MB-231 cells with an IC₅₀ of 26 nM .

HY-44062

G9a-IN-1	Histone Methyltransferase	Inflammation/Immunology Cancer
G9a-IN-1 (Compound 113) is a G9a protein inhibitor. G9A/EHMT2 is a nuclear histone lysine methyltransferase that catalyzes histone H3 lysine 9 dimethylation (H3K9me2), which is a reversible modification generally associated with transcriptional gene silencing. G9a-IN-1 can be used for the research of autoimmune disorders or cancer .

HY-116971

DCG066	Histone Methyltransferase Apoptosis	Cancer
DCG066 is an inhibitor of lysine methyltransferase G9a. DCG066 can bind directly to G9a and inhibit methyltransferase activity in vitro. DCG066 decreases di-methylation levels of histone H3 lysine 9 (H3K9Me2), inhibits cell proliferation and induces cell apoptosis. DCG066 displays low cytotoxicity in leukemia cell lines with high levels of G9a expression, including K562 .

HY-122595

EZH2-IN-1	Histone Methyltransferase	Cancer
EZH2-IN-1 (compound 3) is a selective and SAM-competitive *EZH2* and EZH1 inhibitor with an IC₅₀s of 32 nM, 197 nM and 213 nM for EZH2wt, EZH2 Y641N mutant and EZH1, respectively. EZH2-IN-1 reduces bulk H3K27me3 and H3K27me2 levels. EZH2-IN-1 has the potential for diffuse large B cell lymphoma research .

HY-150510

MS8511	Histone Methyltransferase	Neurological Disease Cancer
MS8511 is a selective G9a/GLP covalent irreversible inhibitor by targeting a cysteine residue at the substrate binding site, with IC₅₀ values of 100 nM (G9a) and 140 nM (GLP), and K_d values of 44 nM (G9a) and 46 nM (GLP). MS8511 reduces the cellular H3K9me2 level and enhances antiproliferation activity. MS8511 can be used for the research of several types of cancers including brain, breast, ovarian, lung, bladder, melanoma, colorectal cancer, and other disease such as Alzheimer’s disease (AD), sickle cell disease, Prader−Willi syndrome (PWS) .

Cat. No.	Product Name	Type

HY-W127629

MOBS	Biochemical Assay Reagents
MOBS is an amphoteric buffer, a butane analogue of the Good buffers MOPS [3-(N-morpholino) propanesulfonic acid] and MES [2-(N-morpholino) ethanesulfonic acid] .

HY-D0858B

MES sodium salt 2-Morpholinoethanesulphonic acid sodium salt	Biochemical Assay Reagents
MES (2-Morpholinoethanesulphonic acid) sodium salt is a buffering agent in biology and biochemistry. MES sodium salt is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES sodium salt is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments ^[2].

HY-D0858

MES 2-Morpholinoethanesulphonic acid	Biochemical Assay Reagents
MES (2-Morpholinoethanesulphonic acid) is a buffering agent in biology and biochemistry. MES is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments ^[2].

HY-D0858A

MES monohydrate 2-Morpholinoethanesulphonic acid monohydrate	Biochemical Assay Reagents
MES (2-Morpholinoethanesulphonic acid) monohydrate is a buffering agent in biology and biochemistry. MES monohydrate is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES monohydrate is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments ^[2].

HY-D0858E

MES potassium 2-Morpholinoethanesulphonic acid potassium	Biochemical Assay Reagents
MES (2-Morpholinoethanesulphonic acid) potassium is a buffering agent in biology and biochemistry. MES potassium is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES potassium is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments ^[2].

HY-D0858C

MES hydrate 2-Morpholinoethanesulphonic acid hydrate	Buffer Reagents
MES (2-Morpholinoethanesulphonic acid) hydrate is a buffering agent in biology and biochemistry. MES hydrate is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES hydrate is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments ^[2].

Cat. No.	Product Name	Target	Research Area

HY-P2256

H3K4(Me2) (1-20)

Peptides Others

H3K4(Me2) (1-20) is a histone peptide. H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage ^[2].
HY-66025

Fmoc-Lys(Me)2-OH hydrochloride

Amino Acid Derivatives Others

Fmoc-Lys(Me)2-OH HCl is a lysine derivative .

HY-P2253

*H3K27(Me2) (15-34)*	Peptides	Cancer
H3K27(Me2) (15-34), a histone peptide, is a repressive chromatin mark derived from human histone. Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of H3K27(Me) ^[2].

HY-P5006

*(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin* d(CH2)5[Tyr(ME)2, Dab5]AVP	Vasopressin Receptor	Cardiovascular Disease
(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin (d(CH2)5[Tyr(Me)2, Dab5]AVP) is a specific antagonist of vasopressin V_1a receptor, with a pA₂ of 6.71 .

HY-P4895

*(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin*	Oxytocin Receptor	Neurological Disease
(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin (OVT) is an oxytocin receptor antagonist. (d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin can be used for the research of neurological disease .

HY-P1162

*(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin* SKF 100273	Vasopressin Receptor	Metabolic Disease
(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin (SKF 100273) is a vasopressin V1 receptor selective antagonist .

HY-P2014

*(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin*	Oxytocin Receptor	Neurological Disease
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin is an oxytocin antagonist and can be used for the research of sexual behavior .

HY-P4397

*(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin*	Oxytocin Receptor	Endocrinology
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, an oxytocin receptor antagonist, abolishes oxytocin-enhanced inhibitory postsynaptic currents in CA1 pyramidal neurons .

Cat. No.	Compare	Product Name	Species	Source

HY-P71918A

	NAD-ME Protein, Human (N-His) Malate dehydrogenase; Malic enzyME 2; Malic enzyME 2 mitochondrial; Malic enzyME 2 NAD+; dependent mitochondrial; Malic enzyME mitochondrial; Malic enzyME NAD+; dependent mitochondrial; MAOM_HUMAN; ME 2; ME2; mitochondrial; NAD dependent malic enzyME mitochondrial; NAD ME; NAD-dependent malic enzyME; NAD-ME; ODS1; Pyruvic malic carboxylase	Human	E. coli
	NAD-ME, a mitochondrial malic enzyme, relies on NAD and catalyzes the oxidative decarboxylation of malate to pyruvate within the mitochondria. Essential for cellular energy metabolism and the tricarboxylic acid (TCA) cycle, NAD-ME links metabolic pathways, influencing energy production and precursor molecule generation. Its enzymatic role is pivotal for balancing cellular redox reactions and meeting the cell's metabolic demands. NAD-ME Protein, Human (N-His) is the recombinant human-derived NAD-ME protein, expressed by E. coli , with C-6*His labeled tag.

Cat. No.	Product Name	Chemical Structure

HY-12033S2

2-Methoxyestradiol-d5

2-Methoxyestradiol-d₅ is the deuterium labeled 2-Hydroxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6][7].

HY-12033S1

2-Methoxyestradiol-13C6

2-Methoxyestradiol- ¹³C₆ is the ¹³C-labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].

HY-12033S

2-Methoxyestradiol-13C,d3

2-Methoxyestradiol- ¹³C,d₃ is the ¹³C- and deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].

HY-D0858S

MES-13d
MES-d₁₃ is the deuterium labeled MES[1]. MES (2-Morpholinoethanesulphonic acid) is a buffering agent in biology and biochemistry. MES is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments[2][3].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80176

	Histone H3 (tri methyl K9) Antibody H3K9ME3; H3 histone family MEmber E pseudogene; H3 histone family, MEmberA; H3/A; H31_HUMAN; H3F3; H3FA; Hist1h3a; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; HIST3H3; histone 1, H3a; Histone cluster 1, H3a; Histone H3 3 pseudogene; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; HistoneH3/l; H3K9ME2; HistoneH3(triMEthylK9)	WB, ICC/IF, IHC-P	Human, Mouse, Rat
	Histone H3 (tri methyl K9) Antibody is a non-conjugated and Mouse origined monoclonal antibody about 15 kDa, targeting to Histone H3 (tri methyl K9). It can be used for WB,ICC,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P83310

ME2 Antibody (YA3055)

ODS1
WB, ICC/IF Human, Mouse, Rat

HY-P80643

	DiMethyl-Histone H3 Antibody (YA783) H3K27ME2; H3 histone; HIST1H3A; Histone cluster 1; H3a	WB, ICC/IF, IP	Human, Mouse, Rat
	DiMethyl-Histone H3 Antibody (YA783) is a non-conjugated and Mouse origined monoclonal antibody about 15 kDa, targeting to DiMethyl-Histone H3 (Lys27) (5F6). It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

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