2309668-29-7

GSK-J1 lithium salt Chemical Structure
2309668-29-7

Chemical Structure

GSK-J1 lithium salt

  • CAS. Nr.: 2309668-29-7
  • Formula:C22H22LiN5O2
  • Molecular Weight:395.38

IUPAC Name: lithium 3-((2-(pyridin-2-yl)-6-(1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)pyrimidin-4-yl)amino)propanoate

InChIKey: WTBLFQHAMMUILY-UHFFFAOYSA-M

SMILES: [Li]OC(CCNC1=NC(C2=NC=CC=C2)=NC(N(CC3)CCC4=C3C=CC=C4)=C1)=O

Biological Activity: GSK-J1 lithium salt is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC50 of 60 nM towards KDM6B.

Art. -Nr. Produktname Reinheit Beschreibung Pricing
HY-15648D 		GSK-J1 lithium salt 98.33% GSK-J1 lithium salt is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC50 of 60 nM towards KDM6B.
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