1373422-53-7
Chemical Structure
GSK-J1
- CAS No.: 1373422-53-7
- Formula:C22H23N5O2
- Molecular Weight:389.45
IUPAC Name: 3-((2-(pyridin-2-yl)-6-(1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)pyrimidin-4-yl)amino)propanoic acid
InChIKey: AVZCPICCWKMZDT-UHFFFAOYSA-N
SMILES: OC(CCNC1=NC(C2=NC=CC=C2)=NC(N(CC3)CCC4=C3C=CC=C4)=C1)=O
Biological Activity: GSK-J1, a chemical probe, is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC50 of 60 nM towards KDM6B.
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
GSK-J1 | 99.79% | GSK-J1, a chemical probe, is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC50 of 60 nM towards KDM6B. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.91
HY-15648DGSK-J1 lithium salt -
Similarity Score 0.91
HY-15648GGSK-J1 sodium -
Similarity Score 0.89
HY-15648BRGSK-J4 (Standard) -
Similarity Score 0.89
HY-15648FRGSK-J4 hydrochloride (Standard) -
Similarity Score 0.82
HY-15648AGSK-J2 -
Similarity Score 0.75
HY-15648IGSK-J2 sodium -
Similarity Score 0.74
HY-15648CGSK-J5 -
Similarity Score 0.73
HY-15648HGSK-J5 hydrochloride -
Similarity Score 0.62
HY-156094JMJD3/HDAC-IN-1 -
Explore the MedChemAI to find more analogs