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  4. GSK-J2 sodium

GSK-J2 sodium is the sodium form of GSK-J2 (HY-15648A). GSK-J2 is an isomer of GSK-J1, and does not have any specific activity. GSK-J1 (HY-15648) is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.

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GSK-J2 sodium Chemical Structure

GSK-J2 sodium Chemical Structure

CAS No. : 2108665-15-0

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GSK-J2 sodium Related Antibodies

Top Publications Citing Use of Products

    GSK-J2 sodium purchased from MedChemExpress. Usage Cited in: Front Mol Neurosci. 2017 Mar 13;10:51.  [Abstract]

    GSK-J1 impaired zebrafish hair cell regeneration. 5 dpf larvae are treated with 400 μM Neomycin for 1 h followed by GSK-J1 exposure for 24 in the presence of BrdU. GSK-J1 significantly reduces the numbers of myosinVI-positive (green) hair cells and BrdU-positive (red) replicating cells.

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    Description

    GSK-J2 sodium is the sodium form of GSK-J2 (HY-15648A). GSK-J2 is an isomer of GSK-J1, and does not have any specific activity. GSK-J1 (HY-15648) is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A[1].

    Molecular Weight

    411.43

    Formula

    C22H22N5NaO2
    CAS No.
    SMILES

    O=C(CCNC1=CC(N2CCC3=C(CC2)C=CC=C3)=NC(C4=CN=CC=C4)=N1)O[Na]
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
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    GSK-J2 sodium Related Classifications

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    GSK-J22108665-15-0OthersInactiveIsomerGSK-J1Inhibitorinhibitorinhibit

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