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GSK-J2 sodium

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GSK-J2 sodium is the sodium form of GSK-J2 (HY-15648A). GSK-J2 is an isomer of GSK-J1, and does not have any specific activity. GSK-J1 (HY-15648) is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.

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  • CAS No.: 2108665-15-0
  • Formule: C22H22N5NaO2
  • Masse moléculaire:411.43
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • GSK-J2 sodium Chemical Structure
    GSK-J2 sodium Chemical Structure
  • Experimental Validation Results for GSK-J2 sodium
CAS No.: 2108665-15-0
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  • GSK-J2 sodium Chemical Structure
    GSK-J2 sodium Chemical Structure
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    GSK-J2 sodium purchased from MedChemExpress. Usage Cited in: Front Mol Neurosci. 2017 Mar 13:10:51. [Abstract]

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     GSK-J1 impaired zebrafish hair cell regeneration. 5 dpf larvae are treated with 400 μM Neomycin for 1 h followed by GSK-J1 exposure for 24 in the presence of BrdU. GSK-J1 significantly reduces the numbers of myosinVI-positive (green) hair cells and BrdU-positive (red) replicating cells.

  • GSK-J2 sodium