1 Result for "

MF-268

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MF-268" in MCE Product Catalog:

Cat. No.: HY-105461
CAS No.: 154619-51-9
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

MF 268 is an orally active, blood-brain barrier-permeable acetylcholinesterase (AChE) inhibitor with an IC50 of 9 nM in rats. MF 268 binds to both the catalytic site and the regulatory anionic site of acetylcholinesterase, and increases the extracellular levels of acetylcholine, norepinephrine, dopamine and serotonin in the rat cortex via a dose-dependent pathway. MF 268 exhibits anti-amnesic effects in rats. MF 268 can be used in research related to Alzheimer's disease .
loading...
    loading...