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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
MYT1 kinase
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "MYT1 kinase" in MCE Product Catalog:
1
1 Cited Publications
PD173952 is a tyrosine kinases inhibitor with IC50s of 0.3, 1.7 and 6.6 nM against Lyn, Abl and Csk, respectively. PD173952 is also a potent Myt1 kinase inhibitor with a Ki of 8.1 nM. PD173952 induces apoptosis .
Synonyms: (Rac)-RP-6306
(Rac)-lunresertib (compound 181) is a potent membrane-associated tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1) (Gene name PKMYT1) inhibitor with an IC50 of <10 nM. (Rac)-lunresertib (compound 181) has anticancer effects .
Synonyms: (R)-RP-6306
(R)-lunresertib ((R)-RP-6306) (compound 183) is a membrane-associated tyrosine- and threonine-specific cdc2 inhibitory kinase (Myt1/PKMYT1) inhibitor with an IC50 of 1360 nM. (R)-lunresertib is applicable to Myt1-mediated cancer-related research .
Myt1-IN-1 is a potent membrane-associated tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1) (Gene name PKMYT1) inhibitor with an IC50 of <10 nM. Myt1-IN-1 has anticancer effects (WO2021195782A1; compound 132) .
Cat. No.: HY-145665
CAS No.: 2719748-43-1
Myt1-IN-2 is a potent membrane-associated tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1) (Gene name PKMYT1) inhibitor with an IC50 of <10 nM. Myt1-IN-2 has anticancer effects (WO2021195782A1; compound 28) .
Myt1-IN-3 is a potent membrane-associated tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1) (Gene name PKMYT1) inhibitor with an IC50s of <10 nM (WO2021195782 A1, compound 95) .
Cat. No.: HY-P702926
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: PKMYT1; MYT1 kinase; Protein kinase, Membrane Associated Tyrosine/Threonine 1; PPP1R126; Membrane-Associated Tyrosine- And Threonine-Specific Cdc2-Inhibitory kinase; Protein Phosphatase 1, Regulatory Subunit 126; MYT1; Non-Specific Serine/Threonine Protei
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703602
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PKMYT1; MYT1 kinase; Protein kinase, Membrane Associated Tyrosine/Threonine 1; PPP1R126; Membrane-Associated Tyrosine- And Threonine-Specific Cdc2-Inhibitory kinase; Protein Phosphatase 1, Regulatory Subunit 126; MYT1; Non-Specific Serine/Threonine Protei
Species:
Human
Source:
E. coli
Cat. No.: HY-188057
CAS No.: 3066062-53-8
Sirusertib (WEE1A&Myt1-IN-1) is a dual Wee1A/Myt1 inhibitor, with an IC50 of ≤10 nM against Wee1A and ≤20 nM against Myt1. Sirusertib is applicable for cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
