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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
139 Results for "
NEU
" in MedChemExpress (MCE) Product Catalog:
Products (139)
139 Results for "NEU" in MCE Product Catalog:
5
5 Cited Publications
Target:
Research Areas:
3FAx-Neu5Ac (Compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X .
4
4 Cited Publications
Synonyms: NEU5Ac2en; DANA
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N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Neu5Ac2en) is a potent neuraminidase (sialidase) inhibitor. N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid shows inhibitory activities against human neuraminidase enzymes with IC50s of 143, 43, 61, and 74 μM for NEU1, NEU2, NEU3, and NEU4, respectively. Anti-influenza virus activity .
3
3 Cited Publications
Synonyms: CMP-NEU5Ac sodium salt
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2
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Piromelatine (Neu-P11) is a melatonin MT1/MT2 receptor agonist, serotonin 5-HT1A/5-HT1D agonist, and serotonin 5-HT2B antagonist. Piromelatine (Neu-P11) possesses sleep promoting, analgesic, anti-neurodegenerative, anxiolytic and antidepressant potentials. Piromelatine (Neu-P11) also possesses pain-related P2X3, TRPV1, and Nav1.7 channel-inhibition capacities .
1
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CMP-SiaNAz (CMP-NeuNAz) sodium is a sialic acid nucleotide sugar derivative. CMP-SiaNAz sodium is integrated into the glycosidic chain through the action of STs in the Golgi apparatus, forming SiaNAz substances. CMP-SiaNAz sodium can serve as a substrate for bacterial-derived sialic acid transferases and is used for chemical enzymatic labeling and imaging of cell surface glycosides .
1
Cat. No.: HY-W145561
CAS No.: 159922-54-0
Synonyms: NEU5Ac alpha(2-3)Gal beta MP glycoside
Category:
Human Gut Microbiota Metabolites Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-32264
CAS No.: 160369-85-7
Synonyms: X-NEUNAc
F16 is a potent growth inhibitor of the neu-overexpressing cells and also selectively inhibits proliferation of mammary epithelial as well as a variety of mouse mammary tumor and human breast cancer cell lines.
Cat. No.: HY-P99254
CAS No.: 946832-34-4
Synonyms: 1E10
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Cat. No.: HY-160821A
CAS No.: 335275-62-2
Synonyms: ManNAc-6P sodium salt
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N-Acetylmannosamine 6-phosphate sodium salt is a NanR modulator and an intermediate in the sialic acid pathway. N-Acetylmannosamine 6-phosphate sodium salt disrupts the binding of NanR to the promoter regions of nanAT and nanE, and prevents NanR-mediated transcriptional repression of these loci. N-Acetylmannosamine 6-phosphate sodium salt acts as a key precursor for sialic acid biosynthesis, participating in this process via Neu5Ac-9-P synthase. N-Acetylmannosamine 6-phosphate sodium salt can be used in research related to GNE myopathy .
Cat. No.: HY-164390
CAS No.: 64364-50-7
Synonyms: NEU5Acα2-6Galβ1-4GlcNAc
Target:
6′SLN is a cancer-related extracellular vesicle (EVs) surface glycan that serves as a key form of protein glycosylation in EVs. 6′SLN is also a sialic acid derivative that can interact with hemagglutinins (HAs) from human and avian influenza virus strains, making it useful for research into anti-influenza drugs .
Cat. No.: HY-P990238
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Cat. No.: HY-E70715
The erbB family comprises 4 structurally related receptors: ErbB1 (EGFR), ErbB2 (HER2-neu), ErbB3 and ErbB4. On ligand stimulation, the receptor forms either homodimers or heterodimers, which activate their cytoplasmic domain. ERBB2 775YVMA776 Recombinant Human Active Protein Kinase is a recombinant ERBB2 775YVMA776 protein that can be used to study ERBB2 775YVMA776-related functions .
Synonyms: NEU5Aca2-6GalNAc-a-Ser/Thr
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STn/sialyl-Tn is a sialic acid associated with breast cancer and its expression is closely related to HER2-pos. STn/sialyl-Tn can be used as a marker to count cells in malignant nipple discharge (PND) .
Cat. No.: HY-161943
CAS No.: 3094051-91-6
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NEU3-IN-1 (compound 963) is a NEU3 inhibitor (Ki: 0.12 μM; IC50: 0.31 μM) based on the 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) scaffold and is a C9 biphenylcarbamate derivative. NEU is a human neuraminidase with 4 isozymes; NEU3-IN-1 is an important tool for studying the function of NEU3 isozymes; its amide and triazole linker analogs are selective for NEU1 and NEU4 isozymes, respectively .
Synonyms: Salfaprodil free base; NEU2000
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Nelonemdaz (Salfaprodil free base) is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz is also a free radical scavenger. Nelonemdaz has excellent neuroprotection against NMDA- and free radical-induced cell death .
Cat. No.: HY-N10626
CAS No.: 125139-41-5
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Cat. No.: HY-P1855
CAS No.: 160790-21-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
