2. Inhibitory Antibodies
  3. Racotumomab

Racotumomab  (Synonyms: 1E10)

Cat. No.: HY-P99254 Purity: 99.90%
COA

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Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is an anti-idiotype monoclonal antibody (MAb). Racotumomab reacts to Neu-glycolyl (NeuGc)-containing gangliosides, sulfatides, and other antigens expressed in tumors. Racotumomab is an active anticancer agent for lung cancer.

For research use only. We do not sell to patients.

Racotumomab Chemical Structure

Racotumomab Chemical Structure

CAS No. : 946832-34-4

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Racotumomab Related Antibodies

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Description

Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is an anti-idiotype monoclonal antibody (MAb). Racotumomab reacts to Neu-glycolyl (NeuGc)-containing gangliosides, sulfatides, and other antigens expressed in tumors. Racotumomab is an active anticancer agent for lung cancer[1][2][3].

In Vitro

Racotumomab induces a specific humoral and cellular immune response against the NeuGcGM3 ganglioside present in tumor cells, stimulating the cell death[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Racotumomab Related Antibodies
In Vivo

Racotumomab (50 μg/dose, i.p.) together with Keyhole limpet hemocyanin (KLH) inhibits tumor growth in F3II cell (s.c.) mammary tumor mice model[2].
Racotumomab (50 μg/dose, s.c.) together with Pemetrexed (100 mg/kg) is highly effective against lung nodules in 3LL cell (s.c.) mice xenograft[3].
Racotumomab (50-200 μg/dose, s.c.) shows no significant antitumor effect in 3LL cell (s.c.) mice xenograft[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 3LL cell (s.c.) mice xenograft[3]
Dosage: 50 μg/dose, together with Pemetrexed (100 mg/kg)
Administration: Subcutaneous injection (s.c.)
Result: Reduced lung nodules.
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Racotumomab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 99.90%

COA (231 KB)

Handling Instructions (2659 KB)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Racotumomab946832-34-41E10OthersTumorNSCLClung canceranti-metastaticNeuGcGM33LL cellF3II cellInhibitorinhibitorinhibit

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