1 Result for "

NLRP3-IN-75

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NLRP3-IN-75" in MCE Product Catalog:

Cat. No.: HY-170233
NLRP3-IN-75 is an orally active NLRP3 inhibitor. NLRP3-IN-75 suppresses IL-1β secretion (IC50 = 23 nM). NLRP3-IN-75 selectively inhibits NLRP3 activation by disrupting inflammasome assembly without affecting NLRC4 or AIM2 inflammasomes. NLRP3-IN-75 exhibits superior efficacy in acute peritonitis, diabetic kidney disease and IBD models .
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