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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
NTAQ1
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "NTAQ1" in MCE Product Catalog:
Cat. No.: HY-164891
CAS No.: 2839138-44-0
Target:
Research Areas:
EM12‑FS is a selective covalent molecular glue degrader of NTAQ1 that binds to CRBN with an IC50 of 256 nM. EM12‑FS covalently modifies the His353 residue of CRBN via chemical modification, reshapes the surface conformation of CRBN protein, selectively recruits NTAQ1 to form a ternary complex, and mediates the degradation of NTAQ1 protein in a CRL4 CRBN E3 ubiquitin-proteasome pathway-dependent manner. EM12‑FS can be used in cancer-related research [1] .
Cat. No.: HY-P71174
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTAQ1; N-Terminal Glutamine Amidase 1; C8orf32; WDYHV1; Protein N-Terminal Glutamine Amidohydrolase; Protein NH2-Terminal Glutamine Deamidase; WDYHV Motif-Containing Protein 1; WDYHV Motif Containing 1; N-Terminal Gln Amidase; Nt(Q)-Amidase; FLJ10204; Chr
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
