13 Results for "

Neuromedin B

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "Neuromedin B" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P0241
CAS No.: 87096-84-2
Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals.
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-103286
CAS No.: 204067-01-6
Purity:  99.38%
Target:  

Bombesin Receptor

Research Areas:  

Cancer

PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively; PD176252 is also an agonist of N-Formyl peptide receptor1/2 (FPR1/FPR2), with EC50s of 0.31 and 0.66 μM in HL-60 cells.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-103277A
Purity:  96.20%
Target:  

Bombesin Receptor

BIM 23042 TFA, a certain somatostatin (SS) octapeptide analogue, is a selective neuropeptide neuromedin B receptor (NMB-R, BB1) antagonist. BIM 23042 has 100-fold lower affinity for gastrin-releasing peptide (GRP) receptor (BB2). BIM 23042 inhibits Neuromedin?B?(HY-P0241), ICI 216140 and DPDM-bombesin ethylamide-induced Ca 2+ release .
loading...
    loading...
Cat. No.: HY-116216
CAS No.: 204066-82-0
Purity:  98.78%
Target:  

Bombesin Receptor

Research Areas:  

Cancer

PD 168368 is a potent, competitive, and selective neuromedin B receptor (NMB-R) antagonist with the Ki of 15–45 nM . PD 168368 is neuromedin B receptor (NMBR; IC50=96 nM) / gastrin-releasing peptide receptor (GRPR IC50=3500 nM) antagonist . PD 168368 also is a mixed FPR1/FPR2/FPR3 agonist with EC50s of 0.57, 0.24, and 2.7 nM, respectively .
loading...
    loading...
Cat. No.: HY-P1423A
Target:  

Bombesin Receptor

Research Areas:  

Metabolic Disease Cancer

BA 1 TFA is a potent agonist for the bombesin (BB) family of receptors. BA1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM .
loading...
    loading...
Cat. No.: HY-103277
CAS No.: 111857-96-6
Target:  

Bombesin Receptor

BIM 23042, a certain somatostatin (SS) octapeptide analogue, is a selective neuropeptide neuromedin B receptor (NMB-R, BB1) antagonist. BIM 23042 has 100-fold lower affinity for gastrin-releasing peptide (GRP) receptor (BB2). BIM 23042 inhibits Neuromedin?B?(HY-P0241), ICI 216140 and DPDM-bombesin ethylamide-induced Ca 2+ release .
loading...
    loading...
Cat. No.: HY-P3134A
Research Areas:  

Metabolic Disease

CPN-267 (compound 7b) TFA is a selective neuromedin U receptor 1 (NMUR1) agonist with the EC50 of 0.25 nM. CPN-267 TFA suppresses body weight gain in mice and can be used for study of obesity .
loading...
    loading...
Cat. No.: HY-P10267
CAS No.: 98537-35-0
Neuromedin B-30 is the neuropeptide, which is orignally isolated from porcine brain and spinal cord. , and may exhibit activity in stimulating smooth-muscle. Neuromedin B causes local vasodilation, increases vascular permeability and local hyperalgesia, thereby participating in neurogenic inflammation. Neuromedin B regulates appetite, body temperature, and behavioral responses to stress. Neuromedin B is also involved in regulating smooth muscle contraction and secretory function in the gastrointestinal tract .
loading...
    loading...
Cat. No.: HY-P1423
CAS No.: 183241-31-8
Target:  

Bombesin Receptor

Research Areas:  

Metabolic Disease Cancer

BA 1 is a potent agonist for the bombesin (BB) family of receptors. BA 1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM .
loading...
    loading...
Cat. No.: HY-125075
CAS No.: 185215-75-2
Target:  

Bombesin Receptor

PD 165929 is a high affinity and competitive non-peptide neuromedin-B (NMB) receptor selective antagonist (Ki: 6.3 nM; IC50: 150 nM for rat NMB receptor) .
loading...
    loading...
Cat. No.: HY-P3134
CAS No.: 2241236-26-8
Research Areas:  

Metabolic Disease

CPN-267 (compound 7b) is a selective neuromedin U receptor 1 (NMUR1) agonist with the EC50 of 0.25 nM. CPN-267 suppresses body weight gain in mice and can be used for study of obesity .
loading...
    loading...
Cat. No.: HY-P71349
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TAC3; Tachykinin-3; Prev. NKNB; Neurokinin-B Protein; ZNEUROK1; Preprotachykinin-B; LncZBTB39-1:2; Gamma Tachykinin 3; LncZBTB39; Preprotachykinin B; NKB; Neurokinin Beta; NK3; PRO1155; Neuromedin K; HH10; Tachykinin 3; Tachykinin Precursor 3; Neurokinin
Species:  
Human
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-103286R
CAS No.: 204067-01-6
Research Areas:  

Cancer

PD176252 (Standard) is the analytical standard of PD176252 (HY-103286). This product is intended for research and analytical applications. PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively; PD176252 is also an agonist of N-Formyl peptide receptor1/2 (FPR1/FPR2), with EC50s of 0.31 and 0.66 μM in HL-60 cells.
loading...
    loading...
  • 1