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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
122 Results for "
Nucleophilicity
" in MedChemExpress (MCE) Product Catalog:
Products (122)
122 Results for "Nucleophilicity" in MCE Product Catalog:
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Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning .
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2,6-Dithiopurine (2,6-Dimercaptopurine) is a nucleophilic scavenger for electrophilic carcinogens. 2,6-Dithiopurine abolishes both DNA adduct formation and the initiation of carcinogenesis .
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1 Cited Publications
Cat. No.: HY-W002805
CAS No.: 66572-56-3
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1 Cited Publications
Cat. No.: HY-W002863
CAS No.: 29241-62-1
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5-Bromo-6-chloronicotinic acid is a halogenated nicotinic acid and synthetic starting material that can be used in studies related to organic synthesis .
Cat. No.: HY-79444
CAS No.: 73183-34-3
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DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) is a bicyclic sterically hindered amidine with strong basicity, which possesses multiple properties such as nucleophilicity and coordination ability. DBU is prone to hydrolysis and can undergo addition, substitution, cyclization and other reactions with various substrates to form derivatives containing its scaffold. DBU can also be used as a catalyst .
Synonyms: DL-α-Glycerol phosphate
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Octan-2-yl 2-cyanoacrylate is an alkyl cyanoacrylate monomer, base-sensitive monofunctional 1,1-disubstituted electron-deficient olefin, polymerizable and copolymerizable monomer. Octan-2-yl 2-cyanoacrylate undergoes homopolymerization via nucleophilic initiation with pyridine as initiator. Octan-2-yl 2-cyanoacrylate forms true copolymers with ethyl 2-cyanoacrylate via nucleophilic initiation with pyridine as initiator .
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Pralidoxime iodide is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning .
Cat. No.: HY-19997
CAS No.: 92051-23-5
Synonyms: TATM
Cat. No.: HY-D0980
CAS No.: 138529-46-1
Synonyms: Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin
Category:
Human Gut Microbiota Metabolites Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-W093017
CAS No.: 626-61-9
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4-Chloropyridine is a NNMT (Nicotinamide N-methyltransferase) substrate and suicide inhibition-based protein labeling scaffold precursor.4-Chloropyridine undergoes NNMT-catalyzed pyridine nitrogen methylation to increase C4 electrophilicity, enabling aromatic nucleophilic substitution by NNMT cysteine C159 for covalent NNMT modification and inactivation.4-Chloropyridine can be used for the research of various cancers .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
