94-63-3
94-63-3
Chemical Structure
Pralidoxime iodide
- CAS No.: 94-63-3
- Formula:C7H9IN2O
- Molecular Weight:264.06
IUPAC Name: (E)-2-((hydroxyimino)methyl)-1-methylpyridin-1-ium iodide
InChIKey: QNBVYCDYFJUNLO-UHFFFAOYSA-N
SMILES: C[N+]1=CC=CC=C1/C=N/O.[I-]
Biological Activity: Pralidoxime iodide is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pralidoxime iodide | 98.0% | Pralidoxime iodide is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning. | ||||||||||||||||||||
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Pralidoxime iodide (Standard) | ≥98% | Pralidoxime (iodide) (Standard) is the analytical standard of Pralidoxime (iodide). This product is intended for research and analytical applications. Pralidoxime iodide is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning. | ||||||||||||||||||||
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Pralidoxime chloride (Standard) | ≥98% | Pralidoxime (chloride) (Standard) is the analytical standard of Pralidoxime (chloride). This product is intended for research and analytical applications. Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning. | ||||||||||||||||||||
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Pralidoxime | Pralidoxime is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime is an antidote for organophosphate poisoning. | |||||||||||||||||||||
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Pralidoxime methanesulfonate | Pralidoxime methanesulfonate is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime methanesulfonate reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime methanesulfonate is an antidote for organophosphate poisoning. | |||||||||||||||||||||
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Salicylaldoxime | 99.83% | Salicylaldoxime is an organic compound, that has been used as a reagent for the gravimetric determination and separation of Cooper, Nickel, Palladium, Lead, Bismuth and Zine. The copper complex of Salicylaldoxime has anticancer activity. | ||||||||||||||||||||
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Trigonelline chloride (Standard) | ≥98% | Trigonelline (chloride) (Standard) is the analytical standard of Trigonelline (chloride). This product is intended for research and analytical applications. Trigonelline chloride is an alkaloid with potential antidiabetic activity that can be isolated from Trigonella foenum-graecum L or Leonurus artemisia. Trigonelline chloride is a potent Nrf2 inhibitor that blocks Nrf2-dependent proteasome activity, thereby enhancing apoptosis in pancreatic cancer cells. Trigonelline chloride also has anti-HSV-1, antibacterial, and antifungal activity, and induces ferroptosis. | ||||||||||||||||||||
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TRIA-662 iodide | 99.78% | TRIA-662 (1-Methylnicotinamide chloride) iodide is an endogenous metabolite. TRIA-662 iodide shows antithrombotic and anti-inflammatory activities. | ||||||||||||||||||||
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(Z)-2-Pyridinecarboxamidoxime | (Z)-2-Pyridinecarboxamidoxime is an isomer of 2-Pyridinecarboxamidoxime and also a type of pharmaceutical intermediate. (Z)-2-Pyridinecarboxamidoxime can be used in studies related to organic synthesis. | |||||||||||||||||||||
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4-Carboxy-1-methylpyridin-1-iumiodide | 4-Carboxy-1-methylpyridin-1-iumiodide is a metal-organic framework (MOF). | |||||||||||||||||||||
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4-Carboxy-1-methylpyridin-1-iumchloride | 4-Carboxy-1-methylpyridin-1-iumchloride is a metal-organic framework (MOF). | |||||||||||||||||||||
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RO-1-5237 (Standard) | ≥98% | RO-1-5237 (Standard) is the analytical standard of RO-1-5237. This product is intended for research and analytical applications. RO-1-5237 is a metabolite of Pyridostigmine Bromide, which is a cholinergic and can be used for myasthenia gravis research. | ||||||||||||||||||||
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References
- [1]. Cadieux CL, et al. Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents. Chem Biol Interact. 2016;259(Pt B):133‐141. [Content Brief]
- [2]. Eyer P, Buckley N. Pralidoxime for organophosphate poisoning. Lancet. 2006;368(9553):2110‐2111. [Content Brief]
