92051-23-5
Chemical Structure
Mannose triflate
Synonym(s): TATM
- CAS No.: 92051-23-5
- Formula:C15H19F3O12S
- Molecular Weight:480.36
IUPAC Name: (2S,3S,4S,5R,6R)-6-(acetoxymethyl)-3-(((trifluoromethyl)sulfonyl)oxy)tetrahydro-2H-pyran-2,4,5-triyl triacetate
InChIKey: OIBDVHSTOUGZTJ-PEBLQZBPSA-N
SMILES: CC(O[C@@H]1[C@@H]([C@@H](O[C@@H]([C@H]1OC(C)=O)COC(C)=O)OC(C)=O)OS(C(F)(F)F)(=O)=O)=O
Biological Activity: Mannose triflate is a glucose analog. Mannose triflate is a precursor for 18F-FDG synthesis for PET applications. Mannose triflate binds to 18F via SN2 nucleophilic substitution reaction. Mannose triflate can be used for an imaging technique in detection of cancer[1][2][3].
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Mannose triflate | 99.79% | Mannose triflate is a glucose analog. Mannose triflate is a precursor for 18F-FDG synthesis for PET applications. Mannose triflate binds to 18F via SN2 nucleophilic substitution reaction. Mannose triflate can be used for an imaging technique in detection of cancer. | ||||||||||||||||||||
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- [1]. Yu S.Review of F-FDG Synthesis and Quality Control. Biomed Imaging Interv J. 2006 Oct;2(4):e57
- [2]. Chirakal R, et al. Base-mediated decomposition of a Mannose triflate during the synthesis of 2-deoxy-2-18F-fluoro-D-glucose[J]. Applied radiation and isotopes, 1995, 46(3): 149-155.
- [3]. Claggett SB, et al. Simplified programming and control of automated radiosynthesizers through unit operations. EJNMMI Res. 2013 Jul 15;3(1):53. [Content Brief]
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