1 Result for "

Oxazolonylflavone

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Oxazolonylflavone" in MCE Product Catalog:

Cat. No.: HY-180912
Target:  

CDK Apoptosis

Research Areas:  

Cancer

HS-36 is a highly selective and orally active dual inhibitor of CDK4 and CDK9 with IC50 values of 18.9 and 4.2 nM respectively. HS-36 exhibits nanomolar-level potent activity against various cancer cells, inducing G0/G1 phase arrest and promoting cell apoptosis. HS-36 efficiently inhibits tumor growth in a mouse model of MV-4-11 tumors. HS-36 can be used for the study of acute myeloid leukemia .
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