1 Result for "

PI3Kδ-IN-21

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PI3Kδ-IN-21" in MCE Product Catalog:

Cat. No.: HY-158688
CAS No.: 3048633-11-7
Target:  

PI3K

Research Areas:  

Inflammation/Immunology

PI3Kδ-IN-21 (Compound 31) is a selective inhibitor for phosphoinositide 3-kinases δ (PI3Kδ), with an IC50 of 13.6 nM. PI3Kδ-IN-21 inhibits proliferation and differentation of T cells through PI3K/AKT/mTOR signaling pathway. PI3Kδ-IN-21 exhibits good pharmacokinetic characters in rat model, and attenuates the experimental autoimmune encephalomyelitis in myelin oligodendrocyte glycoprotein (MOG)-induced EAE model .
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