1 Result for "

PMN-MDSCs

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PMN-MDSCs" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P991447

Target:  

VISTA

Research Areas:  

Cancer

Anti-VSIR/VISTA Antibody (SG7) is an antibody targeting VISTA, with a Kd of 0.14 nM for human VISTA and 1 nM for mouse VISTA. Anti-VSIR/VISTA Antibody (SG7) blocks the function of VISTA, prevents VISTA from binding to T cells, restores suppressed T cell activation, and blocks the interactions between VISTA and PSGL-1 as well as VSIG3. Anti-VSIR/VISTA Antibody (SG7) slows tumor growth, reduces PMN-MDSCs, and increases the numbers of CD4 + and CD8 + T cells in the tumor microenvironment. Anti-VSIR/VISTA Antibody (SG7) can be used in studies related to melanoma, colon cancer, and breast cancer .
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