27 Results for "

PNA synthesis

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "PNA synthesis" in MCE Product Catalog:

Cat. No.: HY-W008129
CAS No.: 2584-71-6
H-D-cis-Hyp-OH is a proline derivative and also a substrate of cis-4-hydroxy-D-proline dehydrogenase from Sinorhizobium meliloti. H-D-cis-Hyp-OH serves as a starting material for the synthesis of conformationally constrained pyrrolidine PNA adenine monomers .
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Cat. No.: HY-W718136
CAS No.: 70442-23-8
Synonyms: GlcN6P-Na
D-Glucosamine 6-phosphate (sodium) (GlcN6P-Na) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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Cat. No.: HY-151738
CAS No.: 1935981-35-3
Target:  

ADC Linkers

Research Areas:  

Others

Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-W540122
CAS No.: 186046-81-1
Fmoc-PNA-C (Bhoc)-OH is a cytosine peptide nucleic acid (PNA) monomer protected by Fmoc/Bhoc. Fmoc-PNA-C (Bhoc)-OH can be used for solid-phase synthesis of long-chain PNAs, including the 20-mer PNA targeting Nnmt mRNA and the PNA targeting the tyrosinease gene to inhibit melanogenesis. Fmoc-PNA-C (Bhoc)-OH can be applied in studies related to type 2 diabetes and Escherichia coli infections .
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Cat. No.: HY-W008129R
CAS No.: 2584-71-6
H-D-cis-Hyp-OH (Standard) is the analytical standard of H-D-cis-Hyp-OH. This product is used for research and analytical applications. H-D-cis-Hyp-OH is a proline derivative and also a substrate of the cis-4-hydroxy-D-proline dehydrogenase from the alfalfa rhizobium (Sinorhizobium meliloti). H-D-cis-Hyp-OH can be used as an initial raw material for the synthesis of conformationally restricted pyrrolidine PNA adenine monomers.
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Cat. No.: HY-403689
CAS No.: 1095275-70-9
Research Areas:  

Others

Fmoc-PNA-J(Boc)-OH is a nucleobase-modified PNA monomer (2-aminopyridine PNA monomer M) with Fmoc and Boc protecting groups, used for solid-phase synthesis of PNAs that form stable Hoogsteen triple helices with double-stranded RNA at physiologically relevant conditions .
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Cat. No.: HY-P11688
Research Areas:  

Others

Fmoc-PNA-M (Bhoc)-OH is a standard peptide nucleic acid (PNA) monomer building block. Fmoc-PNA-M (Bhoc)-OH carries two protecting groups, Fmoc and Bhoc, and is specifically designed for solid-phase and automated PNA synthesis. Fmoc-PNA-M (Bhoc)-OH efficiently participates in the construction of sequence-specific PNA probes. Through its protecting group strategy, Fmoc-PNA-M (Bhoc)-OH ensures the accuracy and efficiency of PNA synthesis, and is one of the important raw materials for PNA synthesis at present .
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Cat. No.: HY-P11691
CAS No.: 2101661-88-3
Research Areas:  

Others

Fmoc-PNA-D (tetraBoc)-OH is an Fmoc/Boc-protected diaminopurine peptide nucleic acid (PNA) monomer suitable for standard Fmoc solid-phase synthesis. Fmoc-PNA-D (tetraBoc)-OH carries Boc-protected exocyclic amino groups and can be incorporated into pseudo-complementary PNA oligomers for applications in antigenic peptide nucleic acid and DNA nanotechnology research .
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Cat. No.: HY-W784626
CAS No.: 139166-80-6
Target:  

Drug Intermediate

Research Areas:  

Others

Boc-PNA-T-OH is a thymine-containing peptide nucleic acid monomer and solid-phase synthesis building block .
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Cat. No.: HY-W540123
CAS No.: 186046-82-2
Research Areas:  

Cancer

Fmoc-PNA-A(Bhoc)-OH is a protected peptide nucleic acid (PNA) monomer carrying an adenine base. Fmoc-PNA-A(Bhoc)-OH contains Fmoc and benzhydryloxycarbonyl (Bhoc) protecting groups, and serves as a standard building block designed specifically for solid-phase PNA synthesis. Fmoc-PNA-A(Bhoc)-OH can be efficiently used to synthesize PNA-based sequence-specific hybridization probes. These probes have broad applications in molecular biology research; for example, they can be used in HER2-expressing tumor-related studies, providing tools for disease diagnosis and mechanism exploration .
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Cat. No.: HY-P11681
CAS No.: 163081-03-6
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Boc-PNA-J(Z)-OH is a protected peptide nucleic acid (PNA) monomer used in solid-phase synthesis. Boc-PNA-J(Z)-OH features a 2,6-diaminopurine (J) base, protected by a carboxybenzyl (Z) group, attached to a Boc-protected aminoethylglycinate backbone. Boc-PNA-J(Z)-OH allows for the synthesis of PNA sequences with enhanced binding affinity and stability.
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Cat. No.: HY-P11689
Research Areas:  

Others

Fmoc-PNA-J (Bhoc)-OH is a protected peptide nucleic acid (PNA) monomer building block used for solid-phase synthesis of PNA oligomers. Fmoc-PNA-J (Bhoc)-OH carries Fmoc/Bhoc protecting groups and functions as a standard Fmoc-protected PNA monomer .
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Cat. No.: HY-W784625
CAS No.: 169287-77-8
Target:  

Drug Intermediate

Research Areas:  

Others

Boc-PNA-G(Z)-OH is a peptide nucleic acid (PNA) monomer that is used for the synthesis of peptide nucleic acid oligomers .
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Cat. No.: HY-P11679
CAS No.: 149500-74-3
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Boc-PNA-U-OH is a protected peptide nucleic acid (PNA) monomer containing a uracil base, designed for solid-phase peptide synthesis (SPPS) using the Boc/Z protection strategy. Boc-PNA-U-OH acts as a building block in creating PNA oligomers that are neutral, stable, and used for antisense/antigene applications.
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Cat. No.: HY-P11682
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Boc-PNA-M(Z)-OH is a protected peptide nucleic acid (PNA) monomer used in solid-phase peptide synthesis (SPPS). Boc-PNA-M(Z)-OH consists of an adenyl base protected with a benzyloxycarbonyl (Z) group and a backbone protected with a tert-butyloxycarbonyl (Boc) group, typically used for creating PNA oligomers.
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Cat. No.: HY-P11685
CAS No.: 2245800-85-3
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Fmoc-PNA-thioU(PMB)-OH is a nucleobase-modified peptide nucleic acid (PNA) monomer used in solid-phase synthesis. Fmoc-PNA-thioU(PMB)-OH features a thiouracil base protected with a p-methoxybenzyl (PMB) group on an Fmoc-protected backbone, designed for incorporating modified PNA bases into oligonucleotides to study binding properties.
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Cat. No.: HY-W665456
CAS No.: 959151-70-3
Target:  

Drug Intermediate

Research Areas:  

Others

Fmoc‑PNA‑U‑OH is a peptide nucleic acid monomer that can be used for the synthesis of peptide nucleic acids (PNAs). Fmoc‑PNA‑U‑OH exhibits specific binding to adenine, resistance to enzymatic degradation, and strong hybridization properties. Fmoc‑PNA‑U‑OH can be applied in research fields such as gene diagnosis, molecular biology, and antisense therapy.
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Cat. No.: HY-P11683
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Boc-PNA-D(tetraZ)-OH is a specialized Peptide Nucleic Acid (PNA) monomer used in solid-phase peptide synthesis, featuring a N-tert-butoxycarbonyl (Boc) protected backbone and a 2,6-diaminopurine nucleobase. Boc-PNA-D(tetraZ)-OH helps increase PNA solubility and binding affinity, often used in molecular diagnostics.
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Cat. No.: HY-P11687
CAS No.: 1417611-27-8
Target:  

Drug Intermediate

Research Areas:  

Others

Fmoc-PNA-M(Boc)-OH is a peptide nucleic acid monomer with Fmoc and Boc protecting groups. Fmoc-PNA-M(Boc)-OH can be used for synthesis of peptide nucleic acid .
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Cat. No.: HY-P11684
CAS No.: 172405-61-7
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Fmoc-PNA-C(Boc)-OH is a protected peptide nucleic acid (PNA) monomer for solid-phase synthesis. Fmoc-PNA-C(Boc)-OH possesses Fmoc-protected skeletal amino groups and Boc-protected cytosine bases, designed to construct stable synthetic DNA analogs. Fmoc-PNA-C(Boc)-OH can be used to prepare highly specific, enzyme-stable antisense probes and diagnostic probes.
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