1 Result for "

PROTAC Axl Degrader 2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PROTAC Axl Degrader 2" in MCE Product Catalog:

Cat. No.: HY-144627
CAS No.: 3033401-45-2
Purity:  98.01%
Target:  

PROTACs TAM Receptor Ras

Research Areas:  

Cancer

PROTAC Axl Degrader 2 is an orally active and selective AXL PROTAC degrader with dual activities of AXL kinase inhibition and AXL protein degradation. PROTAC Axl Degrader 2 induces cytoplasmic vacuolization, excessive macropinosome production, oncosis, H-Ras activation, and Rac1-dependent non-apoptotic cell death. PROTAC Axl Degrader 2 inhibits the proliferation and migration of cancer cells, and also suppresses the growth of tumor cell xenografts under in vivo conditions. PROTAC Axl Degrader 2 can be used in research related to breast cancer .
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