3 Results for "

PROTAC BTK Degrader-13

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "PROTAC BTK Degrader-13" in MCE Product Catalog:

Cat. No.: HY-168963
Target:  

PROTACs Btk Itk p38 MAPK

Research Areas:  

Cancer

PROTAC BTK Degrader-13 is a reagent targeting BTK, with a DC50 of 0.27 μM. PROTAC BTK Degrader-13 degrades BTK in a proteasome-dependent manner and inhibits BTK-mediated downstream signaling pathways by reducing the phosphorylation levels of BTK and p38 MAPK. PROTAC BTK Degrader-13 exerts selective cytotoxic effects on BTK-overexpressing lymphoma cells and ITK-positive cells. PROTAC BTK Degrader-13 can be used in studies related to B-cell lymphoma .
loading...
    loading...
Cat. No.: HY-168964
CAS No.: 1957235-61-8
Ethanolamine-Thalidomide-4-OH is an E3 Ligase Ligand-Linker Conjugate composed of an CRBN ligand (HY-103596) and a linker (HY-Y0524), and can be used for synthesis of PROTACs (eg: PROTAC BTK Degrader-13 (HY-168963)) .
loading...
    loading...
Cat. No.: HY-168965
CAS No.: 2668225-98-5
Research Areas:  

Others

BTK ligand 15 is the target protein ligand of PROTAC BTK Degrader-13 (HY-168963). PROTAC BTK Degrader-13 can selectively degrade BTK .
loading...
    loading...