1 Result for "

PROTAC EGFR degrader11

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PROTAC EGFR degrader11" in MCE Product Catalog:

Cat. No.: HY-161633
CAS No.: 3034244-71-5
Target:  

PROTACs EGFR FAK

Research Areas:  

Cancer

PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader for epidermal growth factor receptor (EGFR), with DC50 <100 nM. PROTAC EGFR degrader 11 binds CRBN-DDB1 with a Ki of 36 nM. PROTAC EGFR degrader 11 degrades EGFR, focal adhesion kinase (FAK), and RSK1, inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC50 <100 nM.
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