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Pathways Recommended: PROTAC
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PROTAC EV-A71 Degrader-1

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-182971

    PROTACs Enterovirus Infection
    PROTAC EV-A71 Degrader-1 is a PROTAC degrader targeting EV-A71 3D polymerase, with broad-spectrum activity against a variety of enteroviruses. PROTAC EV-A71 Degrader-1 induces the degradation of EV-A71 3D polymerase through the ubiquitin-proteasome and autophagy-lysosome pathways, and blocks viral replication. PROTAC EV-A71 Degrader-1 protects infected mice from death, alleviates tissue damage, and exhibits safety profiles. PROTAC EV-A71 Degrader-1 can be used in the research of enterovirus infections. (Pink: EV-A71 ligand (HY-19339); Blue: E3 ligase ligand (HY-W012479); Black: linker (HY-W105744)) .
    PROTAC EV-A71 Degrader-1
  • HY-182976

    Target Protein Ligand-Linker Conjugates Others
    Tenovin-3-CO-C9-NH2 is a conjugate of a target protein ligand and a linker, which can be used for the synthesis of PROTAC EV-A71 Degrader-1 (HY-182971) .
    Tenovin-3-CO-C9-NH2

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