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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
PROTAC RNF4 degrader-1
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "PROTAC RNF4 degrader-1" in MCE Product Catalog:
Cat. No.: HY-181692
Research Areas:
PROTAC RNF4 degrader-1 is a RNF4 PROTAC degrader (Kd = 64.5 nM) that degrades RNF4 via the ubiquitin-proteasome system. PROTAC RNF4 degrader-1 induces DNA damage, apoptosis, and exhibits antiproliferative activity in cancer cells. PROTAC RNF4 degrader-1 displays antitumor activity with no obvious side effects in mouse models. PROTAC RNF4 degrader-1 is applicable to the research of hepatocellular carcinoma .
Cat. No.: HY-181693
Research Areas:
CCW16-C2-Boc is a conjugate targeting RNF4, formed by coupling the target protein ligand CCW16 (HY-143346) with a PROTAC Linker. CCW16-C2-Boc can be used to synthesize the PROTAC degrader: PROTAC RNF4 degrader-1 (HY-181693) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
