4 Results for "

PROTAC SAMHD1 Degrader-1

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "PROTAC SAMHD1 Degrader-1" in MCE Product Catalog:

Cat. No.: HY-182970
Research Areas:  

Inflammation/Immunology

PROTAC SAMHD1 Degrader-1 is an orally active targeted SAMHD1 PROTAC degrader, with an IC50 of 6.3 μM against the dNTP hydrolase activity of SAMHD1. PROTAC SAMHD1 Degrader-1 binds to SAMHD1 inside cells and mediates its degradation, with low off-target effects. PROTAC SAMHD1 Degrader-1 inhibits the production of pro-inflammatory cytokines and interferes with the cascade amplification process of inflammatory responses. PROTAC SAMHD1 Degrader-1 delays the progression of pulmonary fibrosis and exerts protective effects on lung tissues. PROTAC SAMHD1 Degrader-1 can be used in pulmonary fibrosis-related research .
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Cat. No.: HY-182973
Research Areas:  

Others

SAMHD1 ligand-1 is a SAMHD1 ligand that can be used for the synthesis of PROTAC SAMHD1 Degrader-1 (HY-182970) .
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Cat. No.: HY-182975
Research Areas:  

Others

E3 Ligase Ligand-linker Conjugate 229 is a conjugate of an E3 ligase ligand and a linker, which can be used for the synthesis of PROTAC SAMHD1 Degrader-1 (HY-182970) .
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Cat. No.: HY-182974
CAS No.: 3033533-52-4
Target:  

Ligands for E3 Ligase

Research Areas:  

Others

DCAF1 binder 3 is a DCAF1 binder and an E3 ligase ligand. DCAF1 binder 3 can be used to synthesize PROTAC SAMHD1 Degrader-1 (HY-182970) .
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