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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
PROTAC XPO1 degrader-1
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "PROTAC XPO1 degrader-1" in MCE Product Catalog:
Cat. No.: HY-170669
CAS No.: 3105680-00-7
PROTAC XPO1 degrader-1 is a CRBN-recruiting PROTAC degrader of exportin 1 (XPO1), with a DC50 of 23.67 nM. It exerts anti-proliferative effects against acute myeloid leukemia cells by inducing XPO1 protein degradation, inhibiting NF-κB activity, inducing apoptosis, and causing G1 cell cycle arrest. PROTAC XPO1 degrader-1 can be used for research on acute myeloid leukemia .
Cat. No.: HY-170672
CAS No.: 1076236-11-7
Research Areas:
XPO1-ligand-1 is a target protein ligand for XPO1 and can be used to synthesize PROTAC PROTAC XPO1 degrader-1 (HY-170669) .
Cat. No.: HY-170673
CAS No.: 3105679-97-5
Research Areas:
E3 Ligase Ligand-linker Conjugate 156 is a CRBN E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 156 can be used to synthesize PROTAC XPO1 degrader-1 (HY-170669) .
Cat. No.: HY-170671
CAS No.: 1911013-66-5
Target:
Research Areas:
E3 ligase Ligand 49 serves as the E3 ubiquitin ligase ligand for PROTAC XPO1 degrader-1 (HY-170669). E3 ligase Ligand 49 can be utilized for the synthesis of PROTACs .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
