Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
PaPE-1
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "PaPE-1" in MCE Product Catalog:
Cat. No.: HY-167151
CAS No.: 2107327-36-4
Target:
Research Areas:
PaPE-1 is a pathway-preferential estrogen receptor (ER) agonist that preferentially activates ER non-nuclear-initiated signaling while minimally activating nuclear-initiated signaling. PaPE-1 exhibits Ki values of 10 μM and 25 μM for human ERα and ERβ, respectively. The relatively low ER affinity and rapid receptor dissociation of PaPE-1 facilitate the triggering of non-nuclear mTOR/MAPK/AKT signaling, while reducing the recruitment of ERα to chromatin and sustained nuclear ER-dependent transcription. PaPE-1 is suitable for research related to non-nuclear ER signaling, metabolic disorders, ischemic brain injury, Alzheimer's disease, and ER-positive breast cancer [1] .
Cat. No.: HY-157629
CAS No.: 70812-59-8
Synonyms: PaPE; 1-Palmitoyl-2-arachidonoyl PE
Target:
Research Areas:
1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PE (PAPE), a compound isolated from egg yolk with antioxidant activity related to the unsaturated fatty acid content, was extracted, purified, and analyzed by various techniques.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
