1 Result for "

Phthalazinone pyrazole

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Phthalazinone pyrazole" in MCE Product Catalog:

Cat. No.: HY-12564
CAS No.: 880487-62-7
Purity:  ≥98.0%
Research Areas:  

Cancer

Phthalazinone pyrazole is a potent, selective, and orally active inhibitor of Aurora-A kinase with an IC50 of 0.031 μM. Phthalazinone pyrazole can arrests mitosis and subsequently inhibit tumor growth via apoptosis of proliferating cells. Phthalazinone pyrazole suppresses the epithelial-mesenchymal transition (EMT) during the differentiation of hepatocyte-like cells (HLCs) from human embryonic stem cells .
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