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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
471 Results for "
R-3
" in MedChemExpress (MCE) Product Catalog:
Products (471)
471 Results for "R-3" in MCE Product Catalog:
45
45 Publications Verification
Synonyms: DTT; rel-(2R,3R)-1,4-Dimercapto-2,3-butanediol
7
7 Cited Publications
Cat. No.: HY-W015851
CAS No.: 13613-65-5
Synonyms: (R)-(-)-3-Hydroxybutanoic acid sodium; (R)-3-Hydroxybutyric acid sodium
Target:
7
7 Cited Publications
Cat. No.: HY-W051723
CAS No.: 625-72-9
Synonyms: (R)-(-)-3-Hydroxybutanoic acid; (R)-3-Hydroxybutyric acid
Category:
Anti-aging Endocrine diseases Endogenous metabolite Immune System Disorder Ketones, Aldehydes, Acids Other Diseases Disease markers Nervous System Disorder Disease Research Fields Cardiovascular System Disorder
Target:
6
It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
3
3 Cited Publications
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Research Areas:
(1R,3R)-RSL3 is an isomer of RSL3 (HY-100218A). RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells .
3
3 Cited Publications
Cat. No.: HY-W030796A
CAS No.: 150436-68-3
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Research Areas:
Lactisole is a canonical antagonist of sweet taste receptor, selectively targeting to T1R3 subunit, a glucose-sensing receptor. Lactisole inhibits insulin secretion induced by glucose in mouse islets .
3
3 Cited Publications
Cat. No.: HY-W030796
CAS No.: 13794-15-5
Target:
Research Areas:
Lactisole free acid is a canonical antagonist of sweet taste receptor, selectively targeting to T1R3 subunit, a glucose-sensing receptor. Lactisole free acid inhibits insulin secretion induced by glucose in mouse islets .
3
3 Cited Publications
Cat. No.: HY-P0227
CAS No.: 168482-23-3
Target:
Research Areas:
3
Research Areas:
Asenapine (Org 5222) hydrochloride, an atypical antipsychotic, is an antagonist of serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4) and histamine receptors (pKi: 8.2-9.0). Asenapine hydrochloride can be used in the research of schizophrenia and bipolar disorder [2]r .
2
1
It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
1
1
1
1 Cited Publications
Cat. No.: HY-P1531
CAS No.: 72629-65-3
Target:
Research Areas:
1
1 Cited Publications
Target:
Research Areas:
HPA-12 is a blood-brain barrier-permeable small-molecule inhibitor of ceramide transfer protein (CERT) with four stereoisomers (the (1R,3R)-stereoisomer exhibits the highest activity). HPA-12 blocks the transport of ceramide from the endoplasmic reticulum to the Golgi apparatus by binding to the START domain of CERT, leading to intracellular ceramide accumulation and inhibition of sphingomyelin (SM) synthesis. HPA-12 induces endoplasmic reticulum stress via the GRP78/ATF6/CHOP axis and activates mitochondrial autophagy, thereby inhibiting cell growth and inducing apoptosis. In in vivo experiments, HPA-12 significantly reduces the leukemia burden and splenomegaly in mouse models of acute myeloid leukemia (AML) and prolongs survival. HPA-12 is applicable for the research of lipid metabolism in acute myeloid leukemia and Alzheimer's disease [3].
1
1 Cited Publications
Cat. No.: HY-N2541
CAS No.: 122168-40-5
Category:
Triterpenes Terpenoids Asclepiadaceae Metabolic Disease Plants Disease Research Fields Gymnema sylvestre (Retz.) Schult.
Target:
1
1 Cited Publications
Cat. No.: HY-P701744
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PIK3R3; Phosphatidylinositol 3-kinase regulatory subunit gamma; PI3-kinase regulatory subunit gamma; PI3K regulatory subunit gamma; PtdIns-3-kinase regulatory subunit gamma; Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; PI3-kinase subunit p55-gamma; PtdIns-3-kinase regulatory subunit p55-gamma; p55PIK
Species:
Source:
1
Cat. No.: HY-Y1131
CAS No.: 24915-95-5
Synonyms: Ethyl (R)-3-hydroxybutanoate
Cat. No.: HY-W002421
CAS No.: 122536-77-0
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
