1 Result for "

RO2959 monohydrochloride

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RO2959 monohydrochloride" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-113618B
CAS No.: 2309172-44-7
Purity:  98.21%
Research Areas:  

Cardiovascular Disease

RO2959 monohydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 monohydrochloride is a potent blocker of store operated calcium entry (SOCE) mediated by Orai1/Stim1 channels with an IC50 of 25 nM. RO2959 monohydrochloride is also a potent inhibitor of human IL-2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways .
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