1 Result for "

RXR antagonist 6

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RXR antagonist 6" in MCE Product Catalog:

Cat. No.: HY-180181
Target:  

RAR/RXR

Research Areas:  

Metabolic Disease Cancer

RXR antagonist 6 (Compound 34) is a selective partial retinoid X receptor (RXR) antagonist. RXR antagonist 6 shows no agonistic activity for any of the human RXRα/β/γ subtypes but it can strongly inhibit the receptor activation induced by full agonists of RXR (such as Bezafibrate (HY-B0637)) with an IC50 of 2.7 μM. RXR antagonist 6 can enhance PMA (HY-18739)-induced THP-1 cell differentiation. RXR antagonist 6 can be used for the research of cancer, metabolic and neurological disease, such as lymphoma .
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