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Rubrofusarin gentiobioside

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2

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2

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Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-N4177
    Rubrofusarin gentiobioside

    Rubrofusarin-6-β-gentiobioside

    		 Phosphatase Monoamine Oxidase PPAR mTOR AMPK Metabolic Disease
    Rubrofusarin gentiobioside (Rrubrofusarin-6-β-gentiobioside) is an orally active weak inhibitor of PTP1B and MAO-A (IC50 >100 μM), and its glycosylation modification results in lower biological activity than its aglycone Rubrofusarin (HY-130307). Rubrofusarin gentiobioside promotes AMPK phosphorylation in an LKB1-independent manner and inhibits the mTOR signaling pathway, thereby downregulating the expressions of PPARγ, C/EBPα, as well as FAS, LPL and aP2. Rubrofusarin gentiobioside inhibits lipid accumulation, reduces body weight and epididymal white adipose tissue volume, improves fatty liver, and shows no cytotoxicity to hepatocytes. Rubrofusarin gentiobioside is widely used in obesity-related studies .
    Rubrofusarin gentiobioside
  • HY-N15709
    Nor-Rubrofusarin gentiobioside

    		Bacterial Infection
    Nor-Rubrofusarin gentiobioside is a phenolic glycoside de-rubrofusarin that can be isolated from the seeds of Cassia tora. The same series of extracts of Nor-Rubrofusarin gentiobioside have antibacterial effects on Staphylococcus aureus strains .
    Nor-Rubrofusarin gentiobioside

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