1 Result for "

SAR 1118 (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SAR 1118 (Standard)" in MCE Product Catalog:

Cat. No.: HY-19344R
CAS No.: 1025967-78-5
Synonyms: SAR 1118 (Standard); SHP-606 (Standard)
Research Areas:  

Inflammation/Immunology

Lifitegrast (Standard) is the analytical standard of Lifitegrast. This product is intended for research and analytical applications. Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease .
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