Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
SLC13A5
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "SLC13A5" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
PF-06761281 (Compound 4a) is a potent, orally active, partial selective sodium-coupled citrate transporter (NaCT or SLC13A5) inhibitor with IC50 values of 0.51, 13.2 and 14.1 µM against HEKNaCT, HEKNaDC1 and HEKNaDC3, respectively .
1
1 Cited Publications
Target:
Research Areas:
BI 01383298, a chemical probe, is a potent inhibitor of the sodium-citrate co-transporter (SLC13A5) that is highly expressed in the liver .
1
1 Cited Publications
Target:
Research Areas:
PF-06649298 is a sodium-coupled citrate transporter (NaCT or SLC13A5) inhibitor. PF-06649298 specifically interacts with NaCT with an IC50 value of 16.2 μM to inhibits the transport of citrate in human hepatocytes. PF-06649298 can be used for the research of regulating glucose metabolism and lipid metabolism .
Target:
Research Areas:
SLC13A5-IN-1 is a selective sodium-citrate co-transporter (SLC13A5) inhibitor. SLC13A5-IN-1 completely blocks the uptake of 14C-citrate with an IC50 value of 0.022 μM in HepG2 cells. SLC13A5-IN-1 has the potential for the treatment of metabolic and/or cardiovascular diseases. SLC13A5-IN-1 is extracted from patent WO2018104220A1, Compound I-5 .
Cat. No.: HY-RS13009
Target:
Research Areas:
SLC13A5 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC13A5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25066
Target:
Research Areas:
Slc13a5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc13a5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18581
Target:
Research Areas:
Slc13a5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc13a5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-158160
CAS No.: 2918263-09-7
Target:
Research Areas:
LBA-3 is a selective, orally active inhibitor for sodium-coupled citrate transporter SLC13A5, with an IC50 of 67 nM. LBA-3 decreases levels of triglyceride and total cholesterol in oleic and palmitic acid (OPA)-stimulated AML12 cells, PCN-stimulated primary mouse hepatocytes and in mouse models, without detectable toxicity. LBA-3 is blood-brain barrier permeable .
Cat. No.: HY-P703406
Synonyms: SLC13A5; Na+-Coupled Citrate Transporter Protein; Solute Carrier Family 13 Member 5; Sodium-Dependent Citrate Transporter; NACT; Mammalian INDY Homolog (Drosophila); Na(+)/Citrate Cotransporter; Sodium-Coupled Citrate Transporter; MINDY; Mammalian INDY Ho
Species:
Source:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
