NaCT Protein, Human (sf9)
NaCT Protein, Human (sf9) is the recombinant human-derived NaCT, expressed by sf9 insect cells , with tag Free labeled tag. ,
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
NaCT Protein, Human (sf9) is the recombinant human-derived NaCT, expressed by sf9 insect cells , with tag Free labeled tag. ,
NaCT is a high-affinity sodium/citrate cotransporter that mediates cellular citrate uptake, playing critical roles in various biochemical pathways. It transports citrate in a Na(+)-dependent manner, preferentially recognizing the trivalent citrate form at physiological pH over the divalent form. NaCT is implicated in multiple metabolic processes including energy production (Krebs cycle), fatty acid synthesis, cholesterol synthesis, glycolysis, and gluconeogenesis. While capable of recognizing succinate as a substrate, its affinity for succinate is considerably lower than for citrate. The transport process is likely electrogenic with a probable stoichiometry of 4 Na(+) per carboxylate, regardless of substrate valence state. Additionally, NaCT contributes to citrate level regulation in the brain (by similar).
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag Tag Free
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Accession
Q86YT5-1 (M1-T568)
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Gene ID284111
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Protein Length
Full Length of Isoform-1
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Synonyms
SLC13A5; Na+-Coupled Citrate Transporter Protein; Solute Carrier Family 13 Member 5; Sodium-Dependent Citrate Transporter; NACT; Mammalian INDY Homolog (Drosophila); Na(+)/Citrate Cotransporter; Sodium-Coupled Citrate Transporter; MINDY; Mammalian INDY Ho
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AA Sequence
MASALSYVSKFKSFVILFVTPLLLLPLVILMPAKFVRCAYVIILMAIYWCTEVIPLAVTSLMPVLLFPLFQILDSRQVCVQYMKDTNMLFLGGLIVAVAVERWNLHKRIALRTLLWVGAKPARLMLGFMGVTALLSMWISNTATTAMMVPIVEAILQQMEATSAATEAGLELVDKGKAKELPGSQVIFEGPTLGQQEDQERKRLCKAMTLCICYAASIGGTATLTGTGPNVVLLGQMNELFPDSKDLVNFASWFAFAFPNMLVMLLFAWLWLQFVYMRFNFKKSWGCGLESKKNEKAALKVLQEEYRKLGPLSFAEINVLICFFLLVILWFSRDPGFMPGWLTVAWVEGETKYVSDATVAIFVATLLFIVPSQKPKFNFRSQTEEERKTPFYPPPLLDWKVTQEKVPWGIVLLLGGGFALAKGSEASGLSVWMGKQMEPLHAVPPAAITLILSLLVAVFTECTSNVATTTLFLPIFASMSRSIGLNPLYIMLPCTLSASFAFMLPVATPPNAIVFTYGHLKVADMVKTGVIMNIIGVFCVFLAVNTWGRAIFDLDHFPDWANVTHIET
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Predicted Molecular Mass
63.2 kDa
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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