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Results for "

SM

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (17) Acyltransferase (1) ADC Payload (2) Adrenergic Receptor (7) Akt (2) Antibiotic (8) Apoptosis (10) ATF6 (1) Autophagy (1) Bacterial (12) Beta-lactamase (1) Biochemical Assay Reagents (8) c-Kit (1) Calcium Channel (1) Caspase (1) CD20 (1) CD22 (1) CDK (1) Ceramidase (1) Cholinesterase (ChE) (1) CMV (1) DNA Alkylator/Crosslinker (2) DNA/RNA Synthesis (3) Dopamine Receptor (11) Drug Derivative (5) Drug-Linker Conjugates for ADC (1) E1/E2/E3 Enzyme (1) Endogenous Metabolite (7) Endothelin-Converting Enzyme (ECE) (2) ERK (1) Fc Receptor (FcR) (2) FGFR (3) Fluorescent Dye (2) Fungal (4) GHSR (1) Glucocorticoid Receptor (1) GSK-3 (1) HDAC (1) IAP (8) IFNAR (1) Integrin (3) Interleukin Related (2) Isotope-Labeled Compounds (19) Lactate Dehydrogenase (1) Leukotriene Receptor (1) LIM Kinase (LIMK) (3) Liposome (9) mAChR (1) MAP3K (2) MMP (2) mTOR (1) Na+/Ca2+ Exchanger (1) nAChR (1) NADPH Oxidase (1) NF-κB (2) NOD-like Receptor (NLR) (3) Notch (1) Oct3/4 (1) p38 MAPK (1) PACAP Receptor (1) Parasite (5) Penicillin-binding protein (PBP) (3) PERK (1) Phospholipase (5) PI3K (1) PKA (1) Potassium Channel (2) Prion Protein (2) Prostaglandin Receptor (1) Radionuclide-Drug Conjugates (RDCs) (2) Reference Standards (8) Ribosomal S6 Kinase (RSK) (2) Small Interfering RNA (siRNA) (4) Src (2) STAT (1) TGF-β Receptor (1) Toll-like Receptor (TLR) (4) Topoisomerase (3) TSH Receptor (1) VDAC (1) Virus Protease (1) Wnt (3)
By Research Areas:	Cancer (52) Cardiovascular Disease (9) Endocrinology (1) Infection (26) Inflammation/Immunology (26) Metabolic Disease (17) Neurological Disease (38)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Cationic Lipids (4) Human Pre-designed siRNA Sets (1) siRNAs (2)

175

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-134541

SM-102 40+ Cited Publications	Liposome	Infection
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-13678

Meropenem Maximum Cited Publications 32 Publications Verification SM 7338	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection Cancer
Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL) .

HY-15989

SM-164 Maximum Cited Publications 54 Publications Verification	IAP Apoptosis	Cancer
SM-164 is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains with an IC₅₀ value of 1.39 nM and functions as an extremely potent antagonist of XIAP.

HY-13678A

Meropenem trihydrate 30+ Cited Publications SM 7338 trihydrate	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection Cancer
Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL) .

HY-15454

Xevinapant 10+ Cited Publications AT-406; Debio 1143; SM-406	IAP Apoptosis	Cancer
Xevinapant (AT-406) is a potent and orally bioavailable Smac mimetic and an antagonist of IAPs, and it binds to XIAP, cIAP1, and cIAP2 proteins with K_i of 66.4, 1.9, and 5.1 nM, respectively.

HY-N0402

Artemether 3 Publications Verification Dihydroqinghaosu methyl ether; Dihydroartemisinin methyl ether; SM224	Parasite	Infection Inflammation/Immunology Cancer
Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .

HY-137435

Cirtuvivint 2 Publications Verification SM08502	CDK	Cancer
Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor. Cirtuvivint can be used for solid tumors research .

HY-13458

Droxidopa L-DOPS; DOPS; SM5688	Adrenergic Receptor	Cardiovascular Disease Neurological Disease
Droxidopa (L-DOPS; SM5688) is a potent, orally active norepinephrine precursor. Droxidopa increases standing blood pressure, ameliorates symptoms of orthostatic hypotension and improves standing ability. Droxidopa has the potential for the research of neurogenic orthostatic hypotension (nOH) and alternative ADHD (attention deficit hyperactivity disorder) .

HY-B0032A

Lurasidone 10+ Cited Publications SM-13496	5-HT Receptor Dopamine Receptor	Neurological Disease
Lurasidone (SM-13496) is an antagonist of both dopamine D₂ and 5-HT₇ with IC₅₀s of 1.68 and 0.495 nM, respectively. Lurasidone (SM-13496) is also a partial agonist of 5-HT_1A receptor with an IC₅₀ of 6.75 nM.

HY-109049

Adavivint 5+ Cited Publications SM04690; Lorecivivint	Wnt	Inflammation/Immunology Cancer
Adavivint (SM04690; Lorecivivint) is a potent and selective inhibitor of canonical Wnt signaling, with an EC₅₀ of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells .

HY-B0032

Lurasidone Hydrochloride 10+ Cited Publications SM-13496 Hydrochloride	5-HT Receptor Dopamine Receptor	Neurological Disease
Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is an antagonist of both dopamine D₂ and 5-HT₇ with IC₅₀s of 1.68 and 0.495 nM, respectively. Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is also a partial agonist of 5-HT_1A receptor with an IC₅₀ of 6.75 nM.

HY-13678S

Meropenem-d6 SM 7338-d₆	Bacterial Antibiotic	Infection
Meropenem-d₆ is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .

HY-B0061

Tandospirone citrate 3 Publications Verification SM-3997 citrate	5-HT Receptor	Neurological Disease Metabolic Disease
Tandospirone (SM-3997) citrate is a potent and selective 5-HT_1A receptor partial agonist, with a K_i of 27 nM. Tandospirone citrate has anxiolytic and antidepressant activities. Tandospirone citrate can be used for the research of the central nervous system disorders and the underlying mechanisms .

HY-N9480

Vinaxanthone 3 Publications Verification SM-345431	Phospholipase Bacterial	Infection Cancer
Vinaxanthone (SM-345431) is a potent and selective semaphorin3A, phospholipase C (PLC) and FabI inhibitor, with IC₅₀s of 0.1-0.2 μM and 0.9 mM for semaphorin3A and FabI. Vinaxanthone inhibits the substrate (t-o-NAC thioester) and the cofactor (NADPH) with K_is of 3.1 μM and 1.0 μM, respectively. Vinaxanthone can be used to handle infections caused by multidrug-resistant pathogens .

HY-13208

Xevinapant hydrochloride 10+ Cited Publications AT-406 hydrochloride; Debio 1143 hydrochloride; SM-406 hydrochloride	IAP Apoptosis	Cancer
Xevinapant (AT-406) hydrochloride is a potent and orally bioavailable Smac mimetic and an antagonist of the inhibitor of apoptosis proteins (IAPs). Xevinapant hydrochloride binds to XIAP, cIAP1, and cIAP2 proteins with K_is of 66.4, 1.9, and 5.1 nM, respectively. Xevinapant hydrochloride effectively antagonizes XIAP BIR3 protein in a cell-free functional assay, induces rapid degradation of cellular cIAP1 protein, and inhibits cancer cell growth in various human cancer cell lines. Xevinapant hydrochloride is highly effective in induction of apoptosis in xenograft tumors .

HY-136848

SM1-71	MAP3K Src FGFR Ribosomal S6 Kinase (RSK) LIM Kinase (LIMK)	Cancer
SM1-71 (compound 5) is a potent TAK1 inhibitor, with a K_i of 160 nM, it also can covalently inhibit MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2. SM1-71 can inhibit proliferation of multiple cancer cell lines .

HY-14558

Tandospirone 3 Publications Verification SM-3997	5-HT Receptor	Neurological Disease
Tandospirone (SM-3997) is a potent and selective 5-HT_1A receptor partial agonist, with a K_i of 27 nM. Tandospirone has anxiolytic and antidepressant activities. Tandospirone can be used for the research of the central nervous system disorders and the underlying mechanisms .

HY-116626

SM-7368	NF-κB p38 MAPK MMP	Cancer
SM-7368 is a potent NF-kB inhibitor that targets downstream of MAPK p38 activation . SM-7368 inhibits TNF-α-induced MMP-9 upregulation. SM-7368 can be used for the research of chemotherapies targeting TNF-α-mediated tumor invasion and metastasis .

HY-P991266

SM-17	Interleukin Related	Inflammation/Immunology
SM-17 is a humanized monoclonal antibody inhibitor targeting interleukin 25 (IL-25) and interleukin-17 receptor B (IL17RB). SM-17 is promising for research of immune system diseases .

HY-16325A

Miriplatin 3 Publications Verification SM-11355	DNA Alkylator/Crosslinker	Cancer
Miriplatin (SM-11355) is a chemotherapy agent which belongs to the class of alkylating agents.

HY-B0067

Amrubicin SM-5887	Topoisomerase Bacterial	Cancer
Amrubicin (SM-5887) is a DNA topoisomerase II inhibitor, used for the research of cancer.

HY-111482

SM 16 5 Publications Verification	TGF-β Receptor	Cardiovascular Disease Inflammation/Immunology Cancer
SM 16 is a ALK5/ALK4 kinase inhibitor with K_is of 10 and 1.5 nM, respectively.

HY-135516

Dalosirvat 2 Publications Verification SM-04554; Wnt pathway activator 1	Wnt	Neurological Disease Metabolic Disease Cancer
Dalosirvat (SM-04554) is a potent Wnt activator with an EC₅₀s of 28-29 nM. Dalosirvat can be used in the study of cancer .

HY-135642

SMS1-IN-1	Phospholipase	Inflammation/Immunology
SMS1-IN-1, compound SAPA 1j, is a novel and the most potent sphingomyelin synthase 1 (SMS1) inhibitor with an IC₅₀ value of 2.1 μM. SMS1-IN-1 has the potential for the treatment of atherosclerosis .

HY-15989A

SM-164 hydrochloride Maximum Cited Publications 54 Publications Verification	IAP Apoptosis	Cancer
SM-164 hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains with an IC₅₀ value of 1.39 nM and functions as an extremely potent antagonist of XIAP.

HY-134541GL

SM-102 (GMP Like)	Liposome	Infection
SM-102 (GMP Like) is SM-102 (HY-134541) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-125390

SM-360320 CL-087	Toll-like Receptor (TLR)	Inflammation/Immunology Cancer
SM-360320 (CL-087) is a potent, orally active TLR7 agonist. SM-360320 is a immuno-modulator and exerts an antitumor effect. SM-360320 can act in synergy with DNA vaccines leading to an enhanced Th1 antibody response . SM-360320 can inhibit HCV replication in hepatocytes via a type I IFN-independent mechanism in addition to its IFN-mediated activity .

HY-116940

Sm4 1 Publications Verification	Oct3/4 Notch STAT	Cancer
Sm4 is a selective and orally active SOX18 inhibitor. Sm4 inhibits SOX18-DNA binding (IC₅₀ = 97.5 μM); Sm4 disrupts the SOX18-RBPJ protein-protein interaction (IC₅₀ = 42.3 μM). Sm4 blocks SOX18 DNA binding, disrupts multiple SOX18 protein-protein interactions with RBPJ, DDX1, DDX17, ILF3, SOX7 and STAT1, modulates SOX18 chromatin binding dynamics. Sm4 exerts anti‑angiogenic and anti‑lymphangiogenic effects, reduces tumor vascular density, triggers vascular defects in zebrafish, prolongs survival in mouse metastatic cancer models. Sm4 can be used for the research of breast cancer .

HY-124181

SM-1295	IAP Apoptosis	Cancer
SM-1295 is an inhibitor of apoptosis protein (IAP) antagonist, with K_d values of 3077 nM, 3.2 nM and 9.5 nM for XIAP-BIR3, c-IAP1-BIR3 and c-IAP2-BIR3, respectively .

HY-B1354

Cefpiramide SM-1652 free acid; Wy-44635 free acid	Beta-lactamase Antibiotic Bacterial	Infection
Cefpiramide (SM-1652) free acid is a semisynthetic cephalosporin with broad-spectrum antibacterial activity. Cefpiramide free acid shows strong antibacterial effect on both gram-positive bacteria and gram-negative bacteria. Cefpiramide free acid is moderately susceptible to β-lactamase .

HY-B0731A

Perospirone SM-9018 free base	5-HT Receptor Dopamine Receptor	Neurological Disease
Perospirone (SM-9018 free base) is an orally active antagonist of 5-HT_2A receptor (K_i=0.6 nM) and dopamine D₂ receptor (K_i=1.4 nM), and also a partial agonist of 5-HT_1A receptor (K_i=2.9 nM). Perospirone is an atypical antipsychotic agent and has the potential for schizophrenic disease research .

HY-P99529

Valziflocept BAX1810; TAK-752; SM101	Fc Receptor (FcR)	Inflammation/Immunology
Valziflocept (BAX1810; TAK-752) is a recombinant soluble human FcγRIIb receptor that targets Fc and FcγR. FcγRs bind to and neutralize pathogenic IgG, thereby acting as a "decoy" or "scavenger" receptor that reduces the severity of autoimmune diseases. Valziflocept is used in research on autoimmune diseases such as systemic lupus erythematosus (SLE) .

HY-134541G

SM-102	Liposome	Infection
SM-102 (GMP) is SM-102 (HY-134541) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-134541S6

SM-102-d4	Isotope-Labeled Compounds Liposome	Infection
SM-102-d₄ is the deuterium labeled SM-102 (HY-134541). SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-110207

SM-324405	Toll-like Receptor (TLR)	Inflammation/Immunology
SM-324405 is a TLR7 agonistic antedrug (EC₅₀ = 50 nM), with pEC₅₀ values of 7.3 and 6.6 for human TLR7 and Rat TLR7, respectively. SM-324405 is used for immunoresearch of allergic diseases. An antedrug is defined as a locally active compound that is designed to be rapidly metabolized to an inactive form upon entry into the circulation and prevents systemic toxicity by losing its agonistic activity in a plasmatic environment .

HY-B0798

Cefpiramide sodium SM-1652; Wy-44635	Bacterial Antibiotic	Infection
Cefpiramide sodium (SM-1652; Wy-44635) is a new Pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.

HY-B0731

Perospirone hydrochloride SM-9018	5-HT Receptor Dopamine Receptor	Neurological Disease
Perospirone hydrochloride (SM-9018) is an orally active antagonist of 5-HT_2A receptor (K_i of 0.6 nM) and dopamine D₂ receptor (K_i of 1.4 nM). Perospirone hydrochloride is also a partial agonist of 5-HT_1A receptor (K_i of 2.9 nM). Perospirone hydrochloride is an atypical antipsychotic agent and has the potential for schizophrenic disease research .

HY-137553

β-Aminoarteether SM934 free base	NOD-like Receptor (NLR)	Inflammation/Immunology
β-Aminoarteether (SM934 free base) is an Artemisinin derivative with orally active. β-Aminoarteether can be used for inflammation and autoimmune disease research, such as lupus diseases .

HY-13678AR

Meropenem trihydrate (Standard) SM 7338 trihydrate (Standard)	Penicillin-binding protein (PBP) Reference Standards Bacterial Antibiotic	Infection Cancer
Meropenem (trihydrate) (Standard) is the analytical standard of Meropenem (trihydrate). This product is intended for research and analytical applications. Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL) .

HY-123291

SM-276001	Toll-like Receptor (TLR) IFNAR	Inflammation/Immunology Cancer
SM-276001 is a potent selective TLR7 agonist that can induce antitumor immune responses. SM-276001 is an orally active interferon (IFN) inducer .

HY-P990781

Suciraslimab SM03	CD22 NOD-like Receptor (NLR) Interleukin Related Integrin	Neurological Disease Inflammation/Immunology
Suciraslimab (SM03) is an anti-human CD22 monoclonal antibody. Suciraslimab inhibits NLRP3 and ASC signaling. Suciraslimab suppresses cytokine (IL-1β, IL-12, IL-23) secretion and α4 integrin expression. Suciraslimab improves working memory and neuroinflammation . Suciraslimab isotype control product: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-150286

SM875	Prion Protein	Neurological Disease
SM875 is a cellular prion protein (PrP) degrader (IC₅₀: 7.87 μM). SM875 targets PrP folding intermediates and promotes its degradation through the autophagy-lysosomal pathway. SM875 only acts on nascent, immature PrP molecules and has no effect on mature PrP before synthesis. SM875 can inhibit prion replication and has potential in the study of neurodegenerative diseases (i.e., prion diseases) .

HY-N14827

Xanthofulvin SM-216289	Drug Derivative	Neurological Disease
Xanthofulvin (SM-216289) is an inhibitor of semaphorin 3A. Xanthofulvin blocks its binding to receptors, inhibits growth cone collapse, and accelerates olfactory nerve regeneration in rats in vivo. Xanthofulvin can be used in studies related to traumatic neuronal injury .

HY-B0067A

Amrubicin hydrochloride SM-5887 hydrochloride	Topoisomerase Bacterial	Cancer
Amrubicin (SM-5887) hydrochloride is a DNA topoisomerase II inhibitor, used for the research of cancer.

HY-16325

Miriplatin hydrate SM-11355 hydrate	DNA Alkylator/Crosslinker	Cancer
Miriplatin hydrate (SM-11355 hydrate) is a chemotherapy agent which belongs to the class of alkylating agents.

HY-174229

SM311	LIM Kinase (LIMK)	Neurological Disease Cancer
SM311 (Compound 10), a chemical probe, is a potent selective irreversible LIMK1 inhibitor (EC₅₀=0.045 μM, >30-fold selective over LIMK2). SM311 blocks cofilin phosphorylation and actin cytoskeleton regulation. SM311 is promising for research of neurodegenerative diseases like Fragile X syndrome (FXS) and Alzheimer’s disease, as well as tumor invasion .

HY-110053

Tandospirone hydrochloride SM-3997 hydrochloride	5-HT Receptor	Neurological Disease
Tandospirone (SM-3997) hydrochloride is a potent and selective 5-HT_1A receptor partial agonist, with a K_i of 27 nM. Tandospirone hydrochloride has anxiolytic and antidepressant activities. Tandospirone hydrochloride can be used for the research of the central nervous system disorders and the underlying mechanisms .

HY-14849

PTZ601 Razupenem; SM 216601; SMP 601	Antibiotic Bacterial	Others
PTZ601 (SMP 601) is an antibiotic, which inhibits the gram-positive bacteria, including the Vancomycin (HY-B0671)-resistant Enterococcus faecium (VREF) and Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). PTZ601 exhibits antimicrobial activity in infected mouse models .

HY-13458A

Droxidopa hydrochloride L-DOPS hydrochloride; DOPS hydrochloride; SM5688 hydrochloride	Adrenergic Receptor	Cardiovascular Disease Neurological Disease
Droxidopa (L-DOPS) hydrochloride is a potent, orally active norepinephrine precursor. Droxidopa hydrochloride increases standing blood pressure, ameliorates symptoms of orthostatic hypotension and improves standing ability. Droxidopa hydrochloride has the potential for the research of neurogenic orthostatic hypotension (nOH) and alternative ADHD (attention deficit hyperactivity disorder) .

HY-14940A

(S)-Volinanserin (S)-MDL100907; (S)-M 100907	5-HT Receptor	Neurological Disease
(S)-Volinanserin is an isform of Volinanserin (HY-14940). Volinanserin is a potent and selective antagonist of 5-HT₂ receptor, with a K_i of 0.36 nM, and shows 300-fold selectivity for 5-HT₂ receptor over 5-HT_1c, alpha-1 and DA D₂ receptors. Volinanserin has antipsychotic activity.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-13678

Meropenem Maximum Cited Publications 32 Publications Verification SM 7338	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Beta-lactam Antibiotics Source Classification	Penicillin-binding protein (PBP) Bacterial Antibiotic
Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL) .

HY-N0402

Artemether 3 Publications Verification Dihydroqinghaosu methyl ether; Dihydroartemisinin methyl ether; SM224	Classification of Application Fields Terpenoids Sesquiterpenes Artemisia carvifolia Buch.-Ham. ex Roxb. Plants Compositae Disease Research Fields Source Classification Cancer	Parasite
Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .

HY-N9480

Vinaxanthone 3 Publications Verification SM-345431	Microorganisms Xanthones Classification of Application Fields Phenols Disease Research Fields Cancer Source Classification	Phospholipase Bacterial
Vinaxanthone (SM-345431) is a potent and selective semaphorin3A, phospholipase C (PLC) and FabI inhibitor, with IC₅₀s of 0.1-0.2 μM and 0.9 mM for semaphorin3A and FabI. Vinaxanthone inhibits the substrate (t-o-NAC thioester) and the cofactor (NADPH) with K_is of 3.1 μM and 1.0 μM, respectively. Vinaxanthone can be used to handle infections caused by multidrug-resistant pathogens .

HY-128388

N-Palmitoyldihydrosphingomyelin 16:0 Dihydro SM (d18:0/16:0)	Structural Classification Animals Lipid Source Classification	Biochemical Assay Reagents
N-Palmitoyldihydrosphingomyelin (16:0 Dihydro SM (d18:0/16:0)) is a dihydrosphingomyelin.

HY-N14827

Xanthofulvin SM-216289	Structural Classification Natural Products Microorganisms Source Classification	Drug Derivative
Xanthofulvin (SM-216289) is an inhibitor of semaphorin 3A. Xanthofulvin blocks its binding to receptors, inhibits growth cone collapse, and accelerates olfactory nerve regeneration in rats in vivo. Xanthofulvin can be used in studies related to traumatic neuronal injury .

HY-W754473

Lyso-SM-509	Lipid	Biochemical Assay Reagents
Lyso-SM-509, a sphingomyelin, is a biomarker for Niemann-Pick disease Type C .

HY-N15930

16:0 Propargyl SM (d18:1-16:0)	Lipid	Biochemical Assay Reagents
16:0 propargyl SM (d18:1-16:0) is a clickable sphingolipid.

HY-N10805

Schisanlignone C	Terpenoids Lignans Phenylpropanoids Plants Schisandraceae Schisandra viridis A. C. Smith Source Classification	Others
Schisanlignone C is a chemical component of Schisandra viridis a. c. sm .

HY-177003

SM (d18:1/15:0)	Animals Lipid Source Classification	Phospholipase
SM (d18:1/15:0) is a sphingomyelinase inhibitor. SM (d18:1/15:0) is promising for research of neurodegenerative diseases (e.g., Alzheimer's) and metabolic syndrome .

HY-N16304

14:0 Dihydro SM (d18:0/14:0)	Lipid	Biochemical Assay Reagents
14:0 Dihydro SM (d18:0/14:0) is a sphingomyelin.

HY-N2836

Alepterolic acid	Terpenoids Distephanus angulifolius (DC.) H.Rob. & B.Kahn Diterpenoids Cibotiaceae Plants Source Classification	Others
Alepterolic acid is a Diterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .

HY-N0402R

Artemether (Standard) Dihydroqinghaosu methyl ether (Standard); Dihydroartemisinin methyl ether (Standard); SM224 (Standard)	Structural Classification Terpenoids Sesquiterpenes Artemisia carvifolia Buch.-Ham. ex Roxb. Plants Compositae Source Classification	Reference Standards Parasite
Artemether (Standard) is the analytical standard of Artemether. This product is intended for research and analytical applications. Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .

HY-N15965

16:0 Azidoethyl SM (d18:1/16:0)	Lipid	Biochemical Assay Reagents
16:0 Azidoethyl SM (d18:1/16:0) is a clickable phospholipid.

HY-N10806

Schisanlignone D	Plants Schisandraceae Schisandra viridis A. C. Smith Source Classification	Others
Schisanlignone D is a chemical component of Schisandra viridis a. c. sm .

HY-N3833

Epipterosin L	Structural Classification Terpenoids Sesquiterpenes Distephanus angulifolius (DC.) H.Rob. & B.Kahn Cibotiaceae Plants Source Classification	Others
Epipterosin L is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .

HY-N1573

Pterosin Z	Terpenoids Sesquiterpenes Distephanus angulifolius (DC.) H.Rob. & B.Kahn Cibotiaceae Plants Source Classification	Others
Pterosin Z is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .

HY-N3834

Epipterosin L 2'-O-glucoside	Structural Classification Terpenoids Sesquiterpenes Distephanus angulifolius (DC.) H.Rob. & B.Kahn Cibotiaceae Plants Source Classification	Others
Epipterosin L 2'-O-glucoside is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .

HY-N1572

Pterosin D 3-O-glucoside	Terpenoids Sesquiterpenes Distephanus angulifolius (DC.) H.Rob. & B.Kahn Cibotiaceae Plants Source Classification	Others
Pterosin D 3-O-glucoside is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .

HY-N1808

3-Acetoxy-8(17),13E-labdadien-15-oic acid	Terpenoids Distephanus angulifolius (DC.) H.Rob. & B.Kahn Diterpenoids Cibotiaceae Plants Source Classification	Others
3-Acetoxy-8(17),13E-labdadien-15-oic acid is a Diterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .

HY-N8881

Ethyl(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)acetate Jacaranone ethyl ester	Quinones Erinacea anthyllis Link Benzene Quinones Plants Compositae Source Classification	Others
Ethyl(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)acetate (Jacaranone ethyl ester) is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .

Cat. No.	Product Name	Chemical Structure

HY-13678S

Meropenem-d6
Meropenem-d₆ is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .

HY-134541S6

SM-102-d4
SM-102-d₄ is the deuterium labeled SM-102 (HY-134541). SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-146929S

18:1 SM (d18:1/18:1)-d9
18:1 SM (d18:1/18:1)-d₉ is deuterium labeled 18:1 SM (d18:1/18:1).

HY-N0402S

Artemether-d3
Artemether-d₃ is the deuterium labeled Artemether. Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.

HY-146933S

24:1 SM (d18:1/24:1)-d9
24:1 SM (d18:1/24:1)-d₉ is deuterium labeled 24:1 SM (d18:1/24:1).

HY-146930S

16:1 SM (d18:1/16:1)-d9
16:1 SM (d18:1/16:1)-d₉ is deuterium labeled 16:1 SM (d18:1/16:1).

HY-15660S

Efinaconazole-d4
Efinaconazole-d₄ is the deuterium labeled Efinaconazole. Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively . Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species .

HY-146931S

20:1 SM (d18:1/20:1)-d9
20:1 SM (d18:1/20:1)-d₉ is deuterium labeled 20:1 SM (d18:1/20:1).

HY-141629S2

N-Palmitoyl-D-sphingomyelin-d9
N-Palmitoyl-D-sphingomyelin-d₉ (Sphingomyelin 16:0-d₉) is deuterium labeled N-Palmitoyl-D-sphingomyelin. N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles .

HY-13458S1

Droxidopa-13C2,15N hydrochloride
Droxidopa- ¹³C₂, ¹⁵N (hydrochloride) is deuterium labeled Droxidopa. Droxidopa(L-DOPS), the mixture of Droxidopa (w/w80%) and Pharmaceutical starch (w/w20%), acts as a proagent to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline); Droxidopa(L-DOPS) is capable of crossing the protective blood-brain barrier .

HY-B0032AS

Lurasidone-d8
Lurasidone-d₈ is deuterium labeled Lurasidone. Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively. Lurasidone (SM-13496) is also a partial agonist of 5-HT1A receptor with an IC50 of 6.75 nM.

HY-B0032S

Lurasidone-d8 hydrochloride
Lurasidone-d₈ (hydrochloride) is the deuterium labeled Lurasidone, which is an inhibitor of Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C.

HY-146800S

18:1 SM-d9
18:1 SM-d₉ is deuterium labeled 18:1 SM.

HY-W654010

Lurasidone-d8-1 hydrochloride
Lurasidone-d₈-1 (hydrochloride) is deuterium labeled Lurasidone (Hydrochloride). Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is an antagonist of both dopamine D₂ and 5-HT₇ with IC₅₀s of 1.68 and 0.495 nM, respectively. Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is also a partial agonist of 5-HT_1A receptor with an IC₅₀ of 6.75 nM .

HY-14558S

Tandospirone-d8
Tandospirone-d₈ (SM-3997-d₈) is deuterium labeled Tandospirone. Tandospirone (SM-3997) is a potent and selective 5-HT_1A receptor partial agonist, with a K_i of 27 nM. Tandospirone has anxiolytic and antidepressant activities. Tandospirone can be used for the research of the central nervous system disorders and the underlying mechanisms .

HY-B0731AS

Perospirone-d8

Perospirone-d₈ (SM-9018-d₈ (free base)) is deuterium labeled Perospirone. Perospirone (SM-9018 free base) is an orally active antagonist of 5-HT_2A receptor (K_i=0.6 nM) and dopamine D₂ receptor (K_i=1.4 nM), and also a partial agonist of 5-HT_1A receptor (K_i=2.9 nM). Perospirone is an atypical antipsychotic agent and has the potential for schizophrenic disease research .

HY-146901S

15:0 SM (d18:1/15:0)-d9
15:0 SM (d18:1/15:0)-d₉ is deuterium labeled 15:0 SM (d18:1/15:0).

HY-146932S

22:1 SM (d18:1/22:1)-d9
22:1 SM (d18:1/22:1)-d₉ is deuterium labeled 22:1 SM (d18:1/22:1).

HY-13458S2

Droxidopa-13C6

Droxidopa- ¹³C₆ (L-DOPS- ¹³C₆) is ¹³C labeled Droxidopa. Droxidopa (L-DOPS; SM5688) is a potent, orally active norepinephrine precursor. Droxidopa increases standing blood pressure, ameliorates symptoms of orthostatic hypotension and improves standing ability. Droxidopa has the potential for the research of neurogenic orthostatic hypotension (nOH) and alternative ADHD (attention deficit hyperactivity disorder) .

HY-141629S1

N-Palmitoyl-D-sphingomyelin-13C
N-Palmitoyl-D-sphingomyelin-13C is a deuterated labeled N-Palmitoyl-D-sphingomyelin . N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles .

HY-W768856

Artemether-13C,d3
Artemether- ¹³C,d₃ (Dihydroqinghaosu methyl ether- ¹³C,d₃) is the deuterium and ¹³C-labeled Artemether (HY-N0402). Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .

Cat. No.	Product Name	Target	Research Areas	Chemical Structure