1. Anti-infection
  2. Bacterial

Meropenem trihydrate 

Cat. No.: HY-13678A Purity: 98.62%
Data Sheet SDS Handling Instructions

Meropenem (trihydrate) is a carbapenem antibiotic, which displaying a broad spectrum of antibacterial activity.

For research use only. We do not sell to patients.
Meropenem trihydrate Chemical Structure

Meropenem trihydrate Chemical Structure

CAS No. : 119478-56-7

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 79 In-stock
50 mg USD 72 In-stock
100 mg USD 108 In-stock
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500 mg   Get quote  

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Other Forms of Meropenem trihydrate:

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  • Technical Information

  • Purity & Documentation

  • References

Description

Meropenem (trihydrate) is a carbapenem antibiotic, which displaying a broad spectrum of antibacterial activity. Target: Antibacterial Meropenem (trihydrate), a new parenteral carbapenem demonstrated increased activity as compared to imipenem against 336 strains of Neisseria gonorrhoeae, 119 strains of Haemophilus influenzae, and 110 strains of H. Ceftriaxone and ciprofloxacin demonstrated activity superior to that of both carbapenems while the activity of ceftazidime was similar to that of meropenem [1]. Meropenem (trihydrate), like imipenem and various experimental penems, may overcome the resistance problems presented by Class I beta-lactamases [2]. Meropenem (trihydrate) was rapidly penetrated to the pleural effusion and was retained for a more prolonged time in the pleural effusion than in the blood of patients with accumulated pleural effusion, and it suggested the usefulness of Meropenem (trihydrate) in antibacterial therapy for patients with pleurisy causing accumulation of pleural effusion [3]. Clinical indications: Appendicitis; Bacterial infection; Bacterial meningitis; Bacterial pneumonia; Bacterial respiratory tract infection; Bacterial skin infection; Bacterial urinary tract infection; Bacteroides fragilis infection; Bacteroides infection; Bacteroides thetaiotaomicron infection; Complicated skin and skin structure infection FDA Approved Date: July 1996 Toxicity: In mice and rats, large intravenous doses of meropenem (2200-4000 mg/kg) have been associated with ataxia, dyspnea, convulsions, and mortalities.

Clinical Trial
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References
Molecular Weight

437.51

Formula

C₁₇H₃₁N₃O₈S

CAS No.

119478-56-7

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Meropenem trihydrate
Cat. No.:
HY-13678A
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