1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Imipenem monohydrate

Imipenem monohydrate (Synonyms: N-Formimidoyl thienamycin monohydrate)

Cat. No.: HY-B1369 Purity: 98.53%
Handling Instructions

Imipenem monohydrate, a member of the carbapenem class of antibiotics isolated from the soil organism Streptomyces cattleya, is an intravenous β-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria, including several multi-drug resistant bacterial species. Imipenem acts as cell wall-targeting antibiotic.

For research use only. We do not sell to patients.

Imipenem monohydrate Chemical Structure

Imipenem monohydrate Chemical Structure

CAS No. : 74431-23-5

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Estimated Time of Arrival: December 31
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Customer Review

Based on 4 publication(s) in Google Scholar

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  • Purity & Documentation

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Description

Imipenem monohydrate, a member of the carbapenem class of antibiotics isolated from the soil organism Streptomyces cattleya[1], is an intravenous β-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria, including several multi-drug resistant bacterial species. Imipenem acts as cell wall-targeting antibiotic[2][3].

In Vitro

Imipenem is too unstable: 10% degradation at 25°C after 3.5 h[4].
The degradation rate constant of Imipenem is temperature dependent[5].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

317.36

Formula

C12H19N3O5S

CAS No.
SMILES

O=C(C(N12)=C(SCCNC=N)C[[email protected]]2([H])[[email protected]@H]([[email protected]](O)C)C1=O)O.O

Structure Classification
Source

Streptomyces cattleya

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

H2O : 7.14 mg/mL (22.50 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1510 mL 15.7550 mL 31.5100 mL
5 mM 0.6302 mL 3.1510 mL 6.3020 mL
10 mM 0.3151 mL 1.5755 mL 3.1510 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 98.53%

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Imipenem monohydrate
Cat. No.:
HY-B1369
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