1467093-03-3
1467093-03-3
Chemical Structure
Adavivint
Synonym(s): SM04690; Lorecivivint
- CAS No.: 1467093-03-3
- Formula:C29H24FN7O
- Molecular Weight:505.55
IUPAC Name: N-(5-(3-(7-(3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2-yl)-1H-indazol-5-yl)pyridin-3-yl)-3-methylbutanamide
InChIKey: AQDWDWAYVBQMAM-UHFFFAOYSA-N
SMILES: CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN=C1)=O
Biological Activity: Adavivint (SM04690; Lorecivivint) is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells[1].
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Adavivint | 98.85% | Adavivint (SM04690; Lorecivivint) is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells. | ||||||||||||||||||||
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Adavivint (Standard) | ≥98% | Adavivint (Standard) is the analytical standard of Adavivint (HY-109049). This product is intended for research and analytical applications. Adavivint (SM04690; Lorecivivint) is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells. | ||||||||||||||||||||
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