211 Results for "

SPP

" in MedChemExpress (MCE) Product Catalog:
Products (211)

211 Results for "SPP" in MCE Product Catalog:

20
20 Publications Verification
Art. -Nr.: HY-W009168
CAS. Nr.: 89785-84-2
Target:  

Bacterial Antibiotic

Forschungsgebiete:  

Infection Cancer

Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class. Ceftolozane combines with Tazobactam, extends the activity of ceftolozane against many ESBL-producing Enterobacteriaceae and some Bacteroides spp..
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12
12 Cited Publications
Art. -Nr.: HY-16911
CAS. Nr.: 620175-39-5
Synonyms: API-1252; Debio 1452
Target:  

Bacterial Antibiotic

Forschungsgebiete:  

Infection

AFN-1252 is an orally active and selective inhibitor of FabI, an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 exhibits exquisite and highly selective activity against Staphylococcus spp. AFN-1252 exhibits typical MIC90 values of ⩽0.015 μg/ml against diverse clinical isolates of S. aureus. AFN-1252 is efficacious in a mouse model of septicemia providing 100% protection from an otherwise lethal peritoneal infection of S. aureus Smith .
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11
11 Cited Publications
Art. -Nr.: HY-12176
CAS. Nr.: 173334-57-1
Reinheit:  98.78%
Synonyms: CGP 60536; CGP60536B; SPP 100
Target:  

Renin Autophagy

Forschungsgebiete:  

Cardiovascular Disease Cancer

Aliskiren is an orally active, highly potent and selective renin inhibitor, with IC50 of 1.5 nM. Aliskiren can be used for the research of hypertension, cardiovascular diseases and cancer cachexia .
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11
11 Cited Publications
Art. -Nr.: HY-12177
CAS. Nr.: 173334-58-2
Reinheit:  99.62%
Synonyms: CGP 60536 hemifumarate; CGP60536B hemifumarate; SPP 100 hemifumarate
Target:  

Renin Autophagy

Forschungsgebiete:  

Cardiovascular Disease Cancer

Aliskiren (CGP 60536; CGP60536B; SPP 100) hemifumarate is an orally active and selective renin inhibitor, with IC50 of 1.5 nM. Aliskiren hemifumarate can be used for the research of hypertension, cardiovascular diseases and cancer cachexia .
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10
10 Cited Publications
Art. -Nr.: HY-P70499
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Osteopontin; Bone Sialoprotein 1; Nephropontin; Secreted Phosphoprotein 1; SPP-1; Urinary Stone Protein; Uropontin; SPP1; BNSP; OPN
Species:  
Source:  
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5
5 Cited Publications
Art. -Nr.: HY-P78358
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: Osteopontin; Bone sialoprotein 1; Nephropontin; SPP-1; BNSP; OPN; SPP1; Uropontin; BSP-1; ETA-1; BSPI
Species:  
Source:  
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4
4 Cited Publications
Art. -Nr.: HY-108009A
CAS. Nr.: 1631754-41-0
Reinheit:  99.84%
Synonyms: Biafungin acetate; CD101 acetate; SP-3025 acetate
Target:  

Fungal

Forschungsgebiete:  

Infection

Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp. .
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4
4 Cited Publications
Art. -Nr.: HY-12136
CAS. Nr.: 569-77-7
Reinheit:  96.87%
Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC50 of 0.2 μM. Purpurogallin has antioxidant and anti-inflammatory effects .
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4
4 Cited Publications
Art. -Nr.: HY-N8461
CAS. Nr.: 2134-29-4
Synonyms: 3-Hydroxypropionaldehyde; 3-Hydroxypropanal
Reuterin is a broad-spectrum antimicrobial agent active against Gram positive and Gram negative bacteria, as well as yeasts, moulds and protozoa. Reuterin is produced by specific strains of Lactobacillus reuteri during anaerobic metabolism of glycerol. Reuterin also demonstrates potent antimicrobial activity against a broad panel of human and poultry meat campylobacter spp. Isolates .
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3
3 Cited Publications
Art. -Nr.: HY-P0123
CAS. Nr.: 1621717-95-0
Target:  

Peptides

Forschungsgebiete:  

Others

SPACE peptide is a skin penetrating peptide (SPPs). SPACE peptide can enhance topical delivery of a macromolecule, hyaluronic acid .
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3
3 Cited Publications
Art. -Nr.: HY-P71786
Reinheit:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SPP1; Eta-1; Op; SPP-1; Osteopontin; 2AR; Minopontin; Secreted phosphoprotein 1; SPP-1
Species:  
Source:  
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3
3 Cited Publications
Art. -Nr.: HY-B0398
CAS. Nr.: 389-08-2
Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria .
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3
3 Cited Publications
Art. -Nr.: HY-B0398A
CAS. Nr.: 3374-05-8
Forschungsgebiete:  

Infection

Nalidixic acid sodium salt, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria .
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2
2 Cited Publications
Art. -Nr.: HY-110193
CAS. Nr.: 1357349-91-7
Reinheit:  99.71%
Target:  

RET

Forschungsgebiete:  

Cancer

SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC50 of 8 nM. SPP-86 inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling, also inhibits RET-induced estrogen receptorα (ERα) phosphorylation in MCF7 cells . SPP-86 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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2
2 Cited Publications
Art. -Nr.: HY-P80771
Synonyms: SPP1; BNSP; OPN; PSEC0156; Osteopontin; Bone sialoprotein 1; Nephropontin; Secreted phosphoprotein 1; SPP-1; Urinary stone protein; Uropontin

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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2
2 Cited Publications
Art. -Nr.: HY-P79222
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Osteopontin; SPP1; Bone sialoprotein 1; Secreted phosphoprotein 1; SPP-1; 2b7; Secreted Phosphoprotein 1 [BNSP]
Species:  
Rat
Source:  
CHO
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2
2 Cited Publications
Art. -Nr.: HY-B0293A
CAS. Nr.: 64872-76-0
Target:  

Fungal

Forschungsgebiete:  

Infection

Butoconazole, an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole is presumed to function as other imidazole derivatives via inhibition of steroid synthesis .
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2
2 Cited Publications
Art. -Nr.: HY-105048
CAS. Nr.: 204248-78-2
Reinheit:  98.64%
Target:  

Bacterial

Forschungsgebiete:  

Infection

Omiganan is a cationic antimicrobial peptide. Omiganan as an analogue of indolicidin shows activity against gram-positive and gram-negative bacteria but also Candida spp. isolates. Omiganan can be used for the research of alcohol nose and acne .
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2
2 Cited Publications
Art. -Nr.: HY-B0293
CAS. Nr.: 64872-77-1
Synonyms: RS 35887
Target:  

Fungal

Forschungsgebiete:  

Infection

Butoconazole nitrate (RS 35887), an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole nitrate is presumed to function as other imidazole derivatives via inhibition of steroid synthesis .
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2
2 Cited Publications
Art. -Nr.: HY-N7071A
CAS. Nr.: 84878-61-5
Synonyms: Maduramycin ammonium
Maduramicin ammonium (Maduramycin ammonium) is isolated from the actinomycete Actinomadura rubra. Maduramicin ammonium (Maduramycin ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection . Maduramicin ammonium (Maduramycin ammonium) induces cell apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways .
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