569-77-7
569-77-7
Chemical Structure
Purpurogallin
- CAS No.: 569-77-7
- Formula:C11H8O5
- Molecular Weight:220.18
IUPAC Name: 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one
InChIKey: WDGFFVCWBZVLCE-UHFFFAOYSA-N
SMILES: O=C1C(O)=CC=CC2=CC(O)=C(O)C(O)=C21
Biological Activity: Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC50 of 0.2 μM. Purpurogallin has antioxidant and anti-inflammatory effects[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Purpurogallin | 98.06% | Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC50 of 0.2 μM. Purpurogallin has antioxidant and anti-inflammatory effects. | ||||||||||||||||||||
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Purpurogallin (Standard) | ≥98% | Purpurogallin (Standard) is the analytical standard of Purpurogallin. This product is intended for research and analytical applications. Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC50 of 0.2 μM. Purpurogallin has antioxidant and anti-inflammatory effects. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.74
HY-N6877Purpurogallin carboxylic acid -
Similarity Score 0.73
HY-130631SHP2-IN-5 -
Similarity Score 0.67
HY-N7921Urolithin M6 -
Similarity Score 0.66
HY-N09921,6,7-Trihydroxyxanthone -
Similarity Score 0.66
HY-114812Anthrarobin -
Similarity Score 0.66
HY-1154801,3,5-Trihydroxyxanthone -
Similarity Score 0.66
HY-N9341Norswertianin -
Similarity Score 0.65
HY-N9114Mesuaxanthone B -
Similarity Score 0.65
HY-N88911,2,5-Trihydroxyxanthone -
Explore the MedChemAI to find more analogs
References
- [1]. Park HY, et al. Purpurogallin exerts anti‑inflammatory effects in lipopolysaccharide‑stimulated BV2 microglial cells through the inactivation of the NF‑κB and MAPK signaling pathways. Int J Mol Med. 2013 Nov;32(5):1171-8. [Content Brief]
- [2]. Chang CZ, et al. Purpurogallin, a natural phenol, attenuates high-mobility group box 1 in subarachnoid hemorrhage induced vasospasm in a rat model. Int J Vasc Med. 2014;2014:254270. [Content Brief]
- [3]. Honda S, et al. Conversion to purpurogallin, a key step in the mechanism of the potent xanthine oxidase inhibitory activity of pyrogallol. Free Radic Biol Med. 2017 May;106:228-235. [Content Brief]
