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Results for "

SPPS

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetolactate Synthase (ALS) (2) ADC Linker (13) ADC Payload (1) Amino Acid Derivatives (7) AMPK (1) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (31) Apoptosis (9) Autophagy (5) Bacterial (59) Beta-lactamase (1) Biochemical Assay Reagents (4) CDK (1) Cholinesterase (ChE) (3) COX (1) Dihydroorotate Dehydrogenase (3) DNA/RNA Synthesis (7) Drug Derivative (6) Drug Intermediate (9) Drug Metabolite (3) Drug-Linker Conjugates for ADC (1) EGFR (1) Endogenous Metabolite (2) Endothelin Receptor (1) Environmental Pollutants (5) Eukaryotic Initiation Factor (eIF) (1) FAK (1) Fungal (33) Glycosidase (2) Herbicide (1) Integrin (2) Interleukin Related (2) Isotope-Labeled Compounds (12) JAK (1) Mitochondrial Metabolism (4) NF-κB (1) Osteopontin (2) P-glycoprotein (2) Parasite (9) Penicillin-binding protein (PBP) (3) Phosphatase (2) Reactive Oxygen Species (ROS) (1) Reference Standards (22) Renin (3) RET (1) RUNX (1) Sialyltransferase (2) Small Interfering RNA (siRNA) (6) STAT (1) Topoisomerase (4) Xanthine Oxidase (2) γ-secretase (2)
By Research Areas:	Cancer (31) Cardiovascular Disease (11) Endocrinology (1) Infection (95) Inflammation/Immunology (13) Metabolic Disease (10) Neurological Disease (2)
Click Chemistry:	Azide (5) Alkynes (2)
Oligonucleotides:	Rat Pre-designed siRNA Sets (2) Mouse Pre-designed siRNA Sets (2) Human Pre-designed siRNA Sets (2) siRNAs (6)

183

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B2060A

Tiamulin fumarate 1 Publications Verification Thiamutilin fumarate	Bacterial Antibiotic	Infection
Tiamulin (Thiamutilin) fumarate is a diterpenic antibiotic that is widely used in pigs and poultry for the control of infectious diseases. Tiamulin fumarate is effectively used in the study of airsacculitis, which is primarily caused by Mycoplasma spp .

HY-Y1636

Fmoc-Arg(Pbf)-OH	Amino Acid Derivatives Drug Intermediate	Metabolic Disease
Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .

HY-108009A

Rezafungin acetate 3 Publications Verification Biafungin acetate; CD101 acetate; SP-3025 acetate	Fungal	Infection
Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp. .

HY-P990116

*Anti-Mouse osteopontin/SPP1 Antibody (103D6)*	Osteopontin	Inflammation/Immunology
Anti-Mouse osteopontin/SPP1 Antibody (103D6) is a mouse-derived anti-mouse *osteopontin/SPP1* IgG2c κ type antibody inhibitor. Anti-Mouse osteopontin/SPP1 Antibody (103D6) increases cytotoxic T lymphocyte lytic activity and suppresses colon tumor growth. Anti-Mouse osteopontin/SPP1 Antibody (103D6) ameliorates liver injury in common bile duct ligation (CBDL)-induced primary sclerosing cholangitis mice models .

HY-P990117

*Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10)*	Integrin	Cardiovascular Disease Cancer
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived *Osteopontin/SPP1 IgG1* κ type antibody inhibitor. Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) blocks Angiotensin II (HY-13948)-induced DNA synthesis and collagen gel contraction in cardiac fibroblasts. Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) significantly inhibits tumor growth in CT26 or MC38 tumors mice models .

HY-104029

Olorofim F901318	Fungal Dihydroorotate Dehydrogenase	Infection
Olorofim (F901318) selectively inhibits fungal dihydroorotate dehydrogenase (DHODH), a key enzyme in the pyrimidine biosynthesis pathway. Olorofim (F901318). Olorofim exhibits excellent activity against A. fumigatus and other Aspergillus spp. .

HY-126491

SPP-DM1	Drug-Linker Conjugates for ADC	Cancer
SPP-DM1 is a agent-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker SPP .

HY-B2060

Tiamulin 1 Publications Verification Thiamutilin	Bacterial Antibiotic	Infection
Tiamulin (Thiamutilin) is a diterpenic antibiotic that is widely used in pigs and poultry for the control of infectious diseases. Tiamulin is effectively used in the study of airsacculitis, which is primarily caused by Mycoplasma spp .

HY-W009168

Tazobactam sodium Maximum Cited Publications 18 Publications Verification	Bacterial Antibiotic	Infection Cancer
Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class. Ceftolozane combines with Tazobactam, extends the activity of ceftolozane against many ESBL-producing Enterobacteriaceae and some Bacteroides spp..

HY-16911

AFN-1252 10+ Cited Publications API-1252; Debio 1452	Bacterial Antibiotic	Infection
AFN-1252 is an orally active and selective inhibitor of FabI, an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 exhibits exquisite and highly selective activity against Staphylococcus spp. AFN-1252 exhibits typical MIC₉₀ values of ⩽0.015 μg/ml against diverse clinical isolates of S. aureus. AFN-1252 is efficacious in a mouse model of septicemia providing 100% protection from an otherwise lethal peritoneal infection of S. aureus Smith .

HY-108009

Rezafungin Biafungin; CD101; SP-3025	Fungal	Infection
Rezafungin (Biafungin) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp. .

HY-P990795

*Anti-Mouse osteopontin/SPP1 Antibody (100D3)*	Osteopontin	Inflammation/Immunology Cancer
Anti-Mouse osteopontin/SPP1 Antibody (100D3) is an anti-mouse *osteopontin/SPP1* IgG2c monoclonal antibody. Anti-Mouse osteopontin/SPP1 Antibody (100D3) can reverse the inhibition of osteopontin (OPN) on T cells and enhance cytotoxic T lymphocyte (CTL) killing ability. Anti-Mouse osteopontin/SPP1 Antibody (100D3) can improve dentin density. Anti-Mouse osteopontin/SPP1 Antibody (100D3) can be used for researches on cancer and dental related conditions such as colon cancer. The recommend isotype control of Anti-Mouse osteopontin/SPP1 Antibody (100D3): Mouse IgG2c kappa, Isotype Control (HY-P99981) .

HY-N2340

D-(+)-Melezitose (+)-Melezitose; D-Melezitose	Bacterial	Infection
D-(+)-Melezitose can be used to identify clinical isolates of indole-positive and indole-negative Klebsiella spp.

HY-128926

*SPP* 1 Publications Verification N-succinimidyl 4-(2-pyridyldithio) pentanoate	ADC Linker	Cancer
SPP (N-succinimidyl 4-(2-pyridyldithio) pentanoate) is a cleavable disulfide linker, can be used to form cytotoxic compound- linker conjugate .

HY-Y0760

3-Methoxybenzoic acid 3-Anisic acid; NSC 27014; m-Methoxybenzoic acid	Drug Intermediate	Infection
3-Methoxybenzoic acid (3-Anisic acid; NSC 27014; m-Methoxybenzoic acid) is a substituted benzoic acid and precursor for synthesis of hydrazide-hydrazone derivatives active against Gram-positive bacteria, including Bacillus spp .

HY-105048

Omiganan 2 Publications Verification	Bacterial	Infection
Omiganan is a cationic antimicrobial peptide. Omiganan as an analogue of indolicidin shows activity against gram-positive and gram-negative bacteria but also Candida spp. isolates. Omiganan can be used for the research of alcohol nose and acne .

HY-110193

SPP-86 2 Publications Verification	RET	Cancer
SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC₅₀ of 8 nM. SPP-86 inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling, also inhibits RET-induced estrogen receptorα (ERα) phosphorylation in MCF7 cells . SPP-86 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P2148

P-113	Bacterial Antibiotic	Infection Inflammation/Immunology
P-113 is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5. P-113 is active against clinically important microorganisms such as Pseudomonas spp., Staphylococcus spp., and C. albicans .

HY-129034

Ramoplanin	Bacterial Antibiotic	Infection
Ramoplanin is a broad-spectrum lipoglycodepsipeptide antibiotic derived from the Actinoplanes spp with with activity against gram-positive bacteria .

HY-W099729

Ethylhexylglycerin	Bacterial	Inflammation/Immunology
Ethylhexylglycerin has antimicrobial activity, inhibiting the growth of Acinetobacter spp., Pseudomonas aeruginosa complex, and Stenotrophomonas maltophilia. Ethylhexylglycerin can cause pigmentary contact dermatitis .

HY-122071

Bicyclomycin	Antibiotic Bacterial	Infection
Bicyclomycin is an antibiotic. Bicyclomycin exhibits selective antibacterial activity against Gram-negative bacteria such as Escherichia coli and Klebsiella spp., with no cross-resistance. Bicyclomycin is applicable to the research of infectious diseases .

HY-B0643

Dirithromycin 1 Publications Verification LY237216	Bacterial Antibiotic	Infection
Dirithromycin (LY237216), a derivative of Erythromycin, is a potent and orally active semi-synthetic macrolide antibiotic. Dirithromycin is active against gram-positive bacteria, Legionella spp., Helicobacter pylori, and Chlamydia trachomatis .

HY-B1036

Decoquinate	Parasite	Infection
Decoquinate is an orally active, selective inhibitor of the mitochondrial bc1 complex, targeting Eimeria spp. sporozoites and first generation schizonts, and Plasmodium spp. Decoquinate inhibits electron transfer by competitively binding to the mitochondrial cytochrome b system, blocking the parasite's energy metabolism, thereby inhibiting its development and reproduction. Decoquinate has significant anticoccidial activity, preventing intestinal damage and improving host growth performance, and also has inhibitory effects on the liver and blood stages of Plasmodium. Decoquinate is mainly used in veterinary research to prevent and treat coccidiosis in ruminants and poultry .

HY-B0293A

Butoconazole 2 Publications Verification	Fungal	Infection
Butoconazole, an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole is presumed to function as other imidazole derivatives via inhibition of steroid synthesis .

HY-12136

Purpurogallin 4 Publications Verification	Xanthine Oxidase	Cardiovascular Disease Inflammation/Immunology Cancer
Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC₅₀ of 0.2 μM. Purpurogallin has antioxidant and anti-inflammatory effects .

HY-W020785

Fosthiazate	Environmental Pollutants Cholinesterase (ChE)	Others
Fosthiazate is a broad-spectrum nematicide against various plant parasitic nematodes, including Meloidogyne spp., Globodera spp., and Pratylenchus spp., through inhibiting the synthesis of acetylcholinesterase .

HY-111360

SPL-707 1 Publications Verification	γ-secretase	Inflammation/Immunology
SPL-707 is an orally active, selective signal peptide peptidase-like 2a (SPPL2a) inhibitor with an IC₅₀ of 77 nM for hSPPL2a. SPL-707 inhibits γ-secretase (IC₅₀=6.1 μM) and *SPP* (IC₅₀=3.7 μM). SPL-707 has the potential for autoimmune diseases research by targeting B cells and dendritic cells .

HY-126409

Petunidin-3-O-arabinoside chloride	Others	Others
Petunidin-3-O-arabinoside chloride is an anthocyanin with antioxidant activity that can be isolated from blueberry (Vaccinium Spp.) puree .

HY-N6695

Aflatoxicol Aflatoxin R0	Drug Metabolite	Cancer
Aflatoxin (Aflatoxin R0) is a metabolite of aflatoxin B1 produced from Rhizopus spp , and is mutagenic and carcinogenic mycotoxin .

HY-16246

Haloprogin	Fungal	Infection
Haloprogin is a potent antifungal agent. Haloprogin has activity against dermatophytes, Candida spp and a limited number of Gram-positive bacteria .

HY-172888

SPP-037	Endogenous Metabolite Sialyltransferase FAK Integrin	Cancer
SPP-037 is an orally active and selective inhibitor of ST6GAL1 (IC₅₀ = 3.59 μM). SPP-037 inhibits integrin α2,6-sialylation and integrin-FAK-paxillin pathway. SPP-037 inhibits cancer cell proliferation, migration and exhibits antiangiogenic activity. SPP-037 has anti-tumor activity in MDA-MB-231 xenograft mouse model. SPP-037 can be used for the research of triple-negative breast cancer .

HY-RS16219

SPP1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SPP1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for SPP1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

SPP1 Mouse Pre-designed siRNA Set A SPP1 Mouse Pre-designed siRNA Set A

HY-RS13702

SPP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SPP1 Human Pre-designed siRNA Set A contains three designed siRNAs for SPP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SPP1 Human Pre-designed siRNA Set A SPP1 Human Pre-designed siRNA Set A

HY-N9142

Ergosterol glucoside Ergosterol 3-O-β-D-glucopyranoside	Others	Others
Ergosterol glucoside is a steroid that can be isolated from Tuber spp. truffles .

HY-126987

Mesosulfuron-methyl	Environmental Pollutants Acetolactate Synthase (ALS)	Others
Mesosulfuron-methyl is a sulfonylurea herbicide that inhibits acetolactate synthase (ALS) and is used in research for post-emergence control of ryegrass and Avena spp. (wild oat) in wheat fields .

HY-P990227

Anti-Mouse IL-12 Antibody (R1-5D9)	Interleukin Related Bacterial	Infection Inflammation/Immunology
Anti-Mouse IL-12 Antibody (R1-5D9) is a rat-derived IgG2a type antibody inhibitor, targeting to mouse IL-12. Anti-Mouse IL-12 Antibody (R1-5D9) can neutralize IL-12. Anti-Mouse IL-12 Antibody (R1-5D9) can be used for the researches of infection, inflammation and immunology, such as Leishmania infection and skin inflammation .

HY-N1923

Hypaconine	Others	Cardiovascular Disease
Hypaconine is a C19-diterpenoid alkaloid isolated from Aconitum and Delphinium spp. Hypaconine exhibits strong cardiac activity .

HY-136425

Fosetyl-aluminum Fosetyl-Al	Fungal	Infection
Fosetyl-aluminum (Fosetyl-Al) is an active ingredient in many fungicides against downy mildew. Fosetyl-aluminum is used to control many diseases caused by Phytophthora spp. on agricultural and horticultural crops .

HY-N6740

Beta-Zearalanol	Apoptosis	Metabolic Disease
Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .

HY-N4108

Hypophyllanthin	P-glycoprotein	Inflammation/Immunology Cancer
Hypophyllanthin is a major lignan in Phyllanthus spp, with strong anti-inflammatory activity. Hypophyllanthin directly inhibits P-glycoprotein (P-gp) activity and did not interfere with multidrug resistance protein 2 (MRP2) activity .

HY-116479

Citromycetin	Bacterial	Others
Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp .

HY-105282

Eremomycin MM 45289; A 82846A	Antibiotic Bacterial	Infection
Eremomycin (MM 45289) is a potent glycopeptide antibiotic closely related to Vancomycin (HY-B0671). Eremomycin shows antibacterial activity in Staphylococcus spp. and Bacillus subtilis ATCC6633, with the MIC values of 0.03-1.6 μg/mL .

HY-151786

Fmoc-L-Lys(Pentynoyl-DIM)-OH	ADC Linker	Others
Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-W286805

Perinaphthenone Phenalenone	Fungal	Infection
Perinaphthenone has antifungal activity, with IC₅₀s of 36.2 μM (at day 3), 13.3 μM (at day 3), and 39.0 μM (at 60 h) for Botrytis spp., Fusarium spp. and Botryodiplodia spp., respectively .

HY-151679

Fmoc-L-Lys(4-N3-Z)-OH	ADC Linker	Others
Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Lys(4-N3-Z)-OH acts as Lysine building-block for SPPS containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition . Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-129377

Sulfo-SPP	ADC Linker	Cancer
Sulfo-SPP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.

HY-N2340A

D-(+)-Melezitose hydrate (+)-Melezitose hydrate; D-Melezitose hydrate	Bacterial	Infection
D-(+)-Melezitose hydrate ((+)-Melezitose hydrate) can be used to identify clinical isolates of indole-positive and indole-negative Klebsiella spp .

HY-12613

2-C-methylene-myo-inositol oxide NSC 45109	Drug Derivative Fungal	Others
2-C-methylene-myo-inositol oxide (NSC 45109), an inositol derivative, induces pseudohyphae formation in Saccharomyces spp .

HY-151671

Fmoc-L-MeLys(N3)-OH	ADC Linker	Others
Fmoc-L-MeLys(N3)-OH is a click chemistry reagent containing an azide. Fmoc-L-MeLys(N3)-OH is a SPPS building-block for the introduction of N-Me-Lys that can be modified at the N3-group using Click-chemistry . Fmoc-L-MeLys(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-163548

SPP-002	Sialyltransferase	Cancer
SPP-002 is a ST6GAL1 inhibitor with a human IC₅₀ of 16.7 μM. SPP-002 selectively inhibits N-glycan sialylation over O-glycan sialylation and binds strongly to the enzyme active site. SPP-002 suppresses expression of signaling proteins in the integrin/FAK/paxillin pathway. SPP-002 can be used for the research of triple negative breast cancer metastasis .

Cat. No.	Product Name	Type

HY-W019901B

Anhydrous calcium sulfate (97%)

Gypsum ustum (97%)

Biochemical Assay Reagents

Anhydrous calcium sulfate (97%) serves as an oil-based drilling fluid additive and an osteogenic material. Anhydrous calcium sulfate (97%) increases the plastic viscosity, yield point, apparent viscosity and gel strength of oil-based drilling fluids. Anhydrous calcium sulfate (97%) upregulates the expression of bone-related genes FOSL1, RUNX2 and SPP1. Anhydrous calcium sulfate (97%) significantly affects the behavior of dental pulp stem cells, enhancing their proliferation, differentiation and matrix deposition .

Cat. No.	Product Name	Target	Research Area

HY-Y1636

Fmoc-Arg(Pbf)-OH	Amino Acid Derivatives Drug Intermediate	Metabolic Disease
Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .

HY-W010712

Fmoc-His(Trt)-OH 1 Publications Verification	Amino Acid Derivatives	Others
Fmoc-His(Trt)-OH is a histidine derivative with a trityl (Trt) group protecting the His side chain. Fmoc-His(Trt)-OH also has an Fmoc group protecting the α-NH₂ group. Fmoc-His(Trt)-OH can be used in solid-phase peptide synthesis to prevent racemization and byproduct formation. Fmoc-His(Trt)-OH acts as a protected histidine precursor in solid-phase peptide synthesis (SPPS), participating in peptide chain construction through amide bond formation. Fmoc-His(Trt)-OH can be precisely incorporated into the target peptide sequence, ensuring correct peptide chain synthesis and reducing impurity formation. Fmoc-His(Trt)-OH is mainly used in the solid-phase synthesis research of pharmaceutical peptides and bioactive peptides, and is particularly suitable for the preparation of peptide drugs requiring precise control of histidine configuration .

HY-105048

Omiganan 2 Publications Verification	Bacterial	Infection
Omiganan is a cationic antimicrobial peptide. Omiganan as an analogue of indolicidin shows activity against gram-positive and gram-negative bacteria but also Candida spp. isolates. Omiganan can be used for the research of alcohol nose and acne .

HY-P3752

Gly-Ala-Tyr H-Gly-Ala-Tyr-OH	Biochemical Assay Reagents Bacterial	Others
Gly-Ala-Tyr (H-Gly-Ala-Tyr-OH) is a tripeptide substrate composed of L-glycine, alanine, and L-tyrosine joined in sequence by peptide linkages. Gly-Ala-Tyr can be hydrolyzed at both extracellular and intracellular levels by Streptococcus thermophilus, Lactobacillus delbrueckii ssp. bulgaricus, Lactobacillus acidophilus, and Bifidobacterium spp. Ala-Gly-Tyr is functionally related to L-alanine, glycine and L-tyrosine. .

HY-W004864

Fmoc-(S)-2-(4-pentenyl)Ala-OH	Amino Acid Derivatives	Others
Fmoc-(S)-2-(4-pentenyl) Ala-OH is an Fmoc-protected unnatural amino acid. Fmoc-(S)-2-(4-pentenyl) Ala-OH can be used for polypeptide synthesis, such as NYAD-13 (HY-P10834) .

HY-P0123

SPACE peptide 3 Publications Verification	Peptides	Others
SPACE peptide is a skin penetrating peptide (SPPs). SPACE peptide can enhance topical delivery of a macromolecule, hyaluronic acid .

HY-P2148

P-113	Bacterial Antibiotic	Infection Inflammation/Immunology
P-113 is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5. P-113 is active against clinically important microorganisms such as Pseudomonas spp., Staphylococcus spp., and C. albicans .

HY-129034

Ramoplanin	Bacterial Antibiotic	Infection
Ramoplanin is a broad-spectrum lipoglycodepsipeptide antibiotic derived from the Actinoplanes spp with with activity against gram-positive bacteria .

HY-W013781

Boc-Glu(OBzl)-OH	Biochemical Assay Reagents	Others
Boc-Glu(OBzl)-OH (Compound 9) is a glutamic acid derivative commonly used in Boc SPPS. Glutamic acid residues increase the hydrophilicity of the polypeptide and play an important structural and receptor binding role .

HY-P11187

Bactofencin A	Bacterial	Infection
Bactofencin A is a novel class IId bacteriocin. Bactofencin A can be produced by the intestinal isolate Lactobacillus salivarius DPC6502. Bactofencin A displays activity against S. aureus and Listeria spp .

HY-P0068

Aminocandin HMR 3270; IP960; NXL201	Fungal	Infection
Aminocandin (HMR 3270) is water-soluble antifungal agent of the echinocandin class with excellent activity against Aspergillus and Candida spp. .

HY-P11155

Halictine 2	Parasite	Infection
Halictine 2 is an antimicrobial peptide. Halictine 2 exhibits promising anti-parasitic activity against Leishmania spp., targeting both the extracellular infective metacyclic promastigotes and intracellular amastigotes. Halictine 2 can be used for the study of leishmaniases .

HY-W344602

Substance P, [Met-OMet11]	Peptides	Others
Substance P, [Met-OMet11] is a selective *SP-P* agonist. Substance P, [Met-OMet11] also is an active peptide. Substance P, [Met-OMet11] can be used for various biochemical studies .

HY-P4613

Fmoc-D-allo-Thr-OH	Drug Derivative Drug Intermediate	Others
Fmoc-D-allo-Thr-OH is a derivative of D-allothreonine (HY-W001959), which is commonly used as a building block in solid-phase peptide synthesis (SPPS) .

HY-P11679

Boc-PNA-U-OH	DNA/RNA Synthesis	Others
Boc-PNA-U-OH is a protected peptide nucleic acid (PNA) monomer containing a uracil base, designed for solid-phase peptide synthesis (SPPS) using the Boc/Z protection strategy. Boc-PNA-U-OH acts as a building block in creating PNA oligomers that are neutral, stable, and used for antisense/antigene applications.

HY-P11682

Boc-PNA-M(Z)-OH	DNA/RNA Synthesis	Others
Boc-PNA-M(Z)-OH is a protected peptide nucleic acid (PNA) monomer used in solid-phase peptide synthesis (SPPS). Boc-PNA-M(Z)-OH consists of an adenyl base protected with a benzyloxycarbonyl (Z) group and a backbone protected with a tert-butyloxycarbonyl (Boc) group, typically used for creating PNA oligomers.

Cat. No.	Product Name	Target	Research Area	Image

HY-P990116

*Anti-Mouse osteopontin/SPP1 Antibody (103D6)*	Osteopontin	Inflammation/Immunology
Anti-Mouse osteopontin/SPP1 Antibody (103D6) is a mouse-derived anti-mouse *osteopontin/SPP1* IgG2c κ type antibody inhibitor. Anti-Mouse osteopontin/SPP1 Antibody (103D6) increases cytotoxic T lymphocyte lytic activity and suppresses colon tumor growth. Anti-Mouse osteopontin/SPP1 Antibody (103D6) ameliorates liver injury in common bile duct ligation (CBDL)-induced primary sclerosing cholangitis mice models .

HY-P990117

*Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10)*	Integrin	Cardiovascular Disease Cancer
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived *Osteopontin/SPP1 IgG1* κ type antibody inhibitor. Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) blocks Angiotensin II (HY-13948)-induced DNA synthesis and collagen gel contraction in cardiac fibroblasts. Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) significantly inhibits tumor growth in CT26 or MC38 tumors mice models .

HY-P990795

*Anti-Mouse osteopontin/SPP1 Antibody (100D3)*	Osteopontin	Inflammation/Immunology Cancer
Anti-Mouse osteopontin/SPP1 Antibody (100D3) is an anti-mouse *osteopontin/SPP1* IgG2c monoclonal antibody. Anti-Mouse osteopontin/SPP1 Antibody (100D3) can reverse the inhibition of osteopontin (OPN) on T cells and enhance cytotoxic T lymphocyte (CTL) killing ability. Anti-Mouse osteopontin/SPP1 Antibody (100D3) can improve dentin density. Anti-Mouse osteopontin/SPP1 Antibody (100D3) can be used for researches on cancer and dental related conditions such as colon cancer. The recommend isotype control of Anti-Mouse osteopontin/SPP1 Antibody (100D3): Mouse IgG2c kappa, Isotype Control (HY-P99981) .

HY-P990227

Anti-Mouse IL-12 Antibody (R1-5D9)	Interleukin Related Bacterial	Infection Inflammation/Immunology
Anti-Mouse IL-12 Antibody (R1-5D9) is a rat-derived IgG2a type antibody inhibitor, targeting to mouse IL-12. Anti-Mouse IL-12 Antibody (R1-5D9) can neutralize IL-12. Anti-Mouse IL-12 Antibody (R1-5D9) can be used for the researches of infection, inflammation and immunology, such as Leishmania infection and skin inflammation .

HY-P99140

Anti-Mouse IL-1R Antibody (JAMA-147)	Interleukin Related	Infection Metabolic Disease Inflammation/Immunology
Anti-Mouse IL-1R Antibody (JAMA-147) is an anti-mouse IL-1R IgG2b antibody inhibitor derived from host Armenian Hamster. Anti-Mouse IL-1R Antibody (JAMA-147) diminishes Spp1hi-TAM-mediated T cell suppression. Anti-Mouse IL-1R Antibody (JAMA-147) can be used for the researches of inflammation, metabolic disease and infection, such as diabetes .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8461

Reuterin 3 Publications Verification 3-Hydroxypropionaldehyde; 3-Hydroxypropanal	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Bacterial
Reuterin is a broad-spectrum antimicrobial agent active against Gram positive and Gram negative bacteria, as well as yeasts, moulds and protozoa. Reuterin is produced by specific strains of Lactobacillus reuteri during anaerobic metabolism of glycerol. Reuterin also demonstrates potent antimicrobial activity against a broad panel of human and poultry meat campylobacter spp. Isolates .

HY-B0398

Nalidixic acid 2 Publications Verification	Infection Microorganisms Classification of Application Fields Antibiotics Resistance Selection Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic Topoisomerase
Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria .

HY-N2340

D-(+)-Melezitose (+)-Melezitose; D-Melezitose	Infection Polysaccharides Classification of Application Fields Campanulaceae Codonopsis pilosula (Franch.) Nannf. Plants Disease Research Fields Saccharides Source Classification	Bacterial
D-(+)-Melezitose can be used to identify clinical isolates of indole-positive and indole-negative Klebsiella spp.

HY-Y0760

3-Methoxybenzoic acid 3-Anisic acid; NSC 27014; m-Methoxybenzoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Drug Intermediate
3-Methoxybenzoic acid (3-Anisic acid; NSC 27014; m-Methoxybenzoic acid) is a substituted benzoic acid and precursor for synthesis of hydrazide-hydrazone derivatives active against Gram-positive bacteria, including Bacillus spp .

HY-N7071A

Maduramicin ammonium 2 Publications Verification Maduramycin ammonium	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Bacterial Apoptosis Antibiotic Autophagy AMPK Eukaryotic Initiation Factor (eIF)
Maduramicin ammonium (Maduramycin ammonium) is isolated from the actinomycete Actinomadura rubra. Maduramicin ammonium (Maduramycin ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection . Maduramicin ammonium (Maduramycin ammonium) induces cell apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways .

HY-N1136

(+)-Totarol	Infection Animals Classification of Application Fields Terpenoids Diterpenoids Disease Research Fields Source Classification	Bacterial
(+)-Totarol is a diterpenoid membrane-disrupting agent and membrane structure regulator found in plants of the genus Podocarpus spp. (+)-Totarol inserts into phospholipid model membranes, disrupts phospholipid packing, and impairs the functional integrity of membranes. (+)-Totarol exhibits antibacterial activity against a variety of bacterial species and β-lactam-resistant strains, and its action is associated with changes in membrane physical properties. (+)-Totarol can be used in studies related to bacterial infections .

HY-B1419

Salicyl alcohol 2-Hydroxybenzyl alcohol; Saligenin	Structural Classification Monophenols Microorganisms Classification of Application Fields Other Diseases Phenols Disease Research Fields Source Classification	Drug Intermediate Bacterial
Salicyl alcohol (2-Hydroxybenzyl alcohol; Saligenin) is a phenolic alcohol-type topical anesthetic and strong sensitizer with antiseptic, antibacterial and antipyretic activities. Salicyl alcohol serves as a precursor for salicin synthesis. Salicyl alcohol induces contact dermatitis and eczematous skin reactions, and is a well-known allergen identified in phenolic resins. Salicyl alcohol is isolated from the barks of European aspen (Populus tremula), rowan (Sorbus aucuparia) and willow (Salix spp.). Salicyl alcohol is used in studies related to allergic contact dermatitis .

HY-129034

Ramoplanin	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic
Ramoplanin is a broad-spectrum lipoglycodepsipeptide antibiotic derived from the Actinoplanes spp with with activity against gram-positive bacteria .

HY-122071

Bicyclomycin	Structural Classification Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Bicyclomycin is an antibiotic. Bicyclomycin exhibits selective antibacterial activity against Gram-negative bacteria such as Escherichia coli and Klebsiella spp., with no cross-resistance. Bicyclomycin is applicable to the research of infectious diseases .

HY-12136

Purpurogallin 4 Publications Verification	Phenols Polyphenols Plants Fagaceae Inflammation/Immunology Disease Research Fields Macaranga denticulata (Blume) Müll. Arg. Cancer	Xanthine Oxidase
Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC₅₀ of 0.2 μM. Purpurogallin has antioxidant and anti-inflammatory effects .

HY-126409

Petunidin-3-O-arabinoside chloride	Anthocyans Flavonoids other families Classification of Application Fields Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Others
Petunidin-3-O-arabinoside chloride is an anthocyanin with antioxidant activity that can be isolated from blueberry (Vaccinium Spp.) puree .

HY-N9142

Ergosterol glucoside Ergosterol 3-O-β-D-glucopyranoside	Structural Classification Microorganisms Steroids Source Classification	Others
Ergosterol glucoside is a steroid that can be isolated from Tuber spp. truffles .

HY-N1923

Hypaconine	Cardiovascular Disease Alkaloids Classification of Application Fields Other Alkaloids Ranunculaceae Aconitum carmichaeli Debx. Plants Disease Research Fields Source Classification	Others
Hypaconine is a C19-diterpenoid alkaloid isolated from Aconitum and Delphinium spp. Hypaconine exhibits strong cardiac activity .

HY-N6740

Beta-Zearalanol	Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Phenols Polyphenols Metabolic Disease Antibacterial Disease Research Disease Research Fields Source Classification	Apoptosis
Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .

HY-N4108

Hypophyllanthin	Phyllanthus urinaria Linn. Classification of Application Fields Lignans Euphorbiaceae Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields Source Classification	P-glycoprotein
Hypophyllanthin is a major lignan in Phyllanthus spp, with strong anti-inflammatory activity. Hypophyllanthin directly inhibits P-glycoprotein (P-gp) activity and did not interfere with multidrug resistance protein 2 (MRP2) activity .

HY-127072

Amicoumacin A	Structural Classification Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Amicoumacin A is an orally active antibiotic. Amicoumacin A targets bacterial ribosomes and inhibits bacterial translation by stabilizing the interaction between mRNA and ribosomes. Amicoumacin A induces cancer cell death by targeting eukaryotic ribosomes. Amicoumacin A exhibits anti-inflammatory and anti-ulcer activities, inhibits carrageenan-induced paw edema, and prevents stress-induced gastric ulcers. Amicoumacin A inhibits the growth of Gram-positive bacteria, Salmonella spp., Shigella spp., Helicobacter pylori, and methicillin-resistant Staphylococcus aureus. Amicoumacin A can be used in the research of lung cancer, breast cancer, bacterial infections, inflammatory edema and gastric ulcers ^[2] .

HY-116479

Citromycetin	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Marine natural products Other Diseases Phenols Polyphenols Marine microorganism Disease Research Fields Source Classification	Bacterial
Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp .

HY-105282

Eremomycin MM 45289; A 82846A	Microorganisms Antibiotics Source Classification	Antibiotic Bacterial
Eremomycin (MM 45289) is a potent glycopeptide antibiotic closely related to Vancomycin (HY-B0671). Eremomycin shows antibacterial activity in Staphylococcus spp. and Bacillus subtilis ATCC6633, with the MIC values of 0.03-1.6 μg/mL .

HY-N2340A

D-(+)-Melezitose hydrate (+)-Melezitose hydrate; D-Melezitose hydrate	Infection Polysaccharides other families Classification of Application Fields Plants Disease Research Fields Saccharides Source Classification	Bacterial
D-(+)-Melezitose hydrate ((+)-Melezitose hydrate) can be used to identify clinical isolates of indole-positive and indole-negative Klebsiella spp .

HY-W250315

Polypectate sodium pectate sodium	Natural Products Polysaccharides Microorganisms Classification of Application Fields Other Diseases Disease Research Fields Saccharides	Glycosidase Bacterial Endogenous Metabolite
Polypectate sodium is a major component of cell wall polysaccharides (pectins) and is used as a carbon source and inducer of polygalacturonase. Polypectate sodium can also be used to evaluate alkaline active and alkaline stable pectate lyases from Streptomyces spp. and to study the optimization of polygalacturonase production from Xanthophyllum spp. and reaction conditions .

HY-N7071

Maduramicin Maduramycin	Infection Microorganisms Classification of Application Fields Antibiotics Disease Research Fields Polyether Antibiotics Source Classification	Antibiotic Apoptosis
Maduramicin (Maduramycin) is isolated from the actinomycete Actinomadura rubra. Maduramicin is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection . Maduramicin induces cell apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways .

HY-B0398R

Nalidixic acid (Standard)	Structural Classification Microorganisms Antibiotics Resistance Selection Antibacterial Disease Research Other Antibiotics Source Classification	Reference Standards Bacterial Antibiotic Topoisomerase
Nalidixic acid (Standard) is the analytical standard of Nalidixic acid. This product is intended for research and analytical applications. Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria .

HY-N12178

16-Deethylindanomycin A 83094A; Omomycin	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial Parasite
16-Deethylindanomycin (A 83094A) is an antibiotic, which can be produced by Streptomyces setonii. 16-Deethylindanomycin exhibits antimicrobial activities against gram-positive bacteria Staphylococcus spp. and Streptococcus with MIC of 2-4 µg/mL. 16-Deethylindanomycin exhibits anticoccidial activity against Eimeria tenella .

HY-125388

Martinomycin	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Martinomycin is an antibiotic, which inhibits Staphylococcus spp., Streptococcus spp. and Enterococcus spp., with MICs ranging from 0.06 to 0.5 μg/mL .

HY-N11995

allo-Aloeresin D	Monophenols Liliaceae Phenols Aloe vera (L.) Burm. f. Plants Source Classification	Others
allo-Aloeresin D is a chromone glycoside isolated from Aloe spp. .

HY-N15183

Aselacin C	Natural Products Microorganisms Source Classification	Fungal
Aselacin C is a cyclic peptide that can be isolated from the fungus Acremonium spp. .

HY-N2340R

D-(+)-Melezitose (Standard) (+)-Melezitose (Standard); D-Melezitose (Standard)	Structural Classification Polysaccharides Campanulaceae Codonopsis pilosula (Franch.) Nannf. Plants Saccharides Source Classification	Reference Standards Bacterial
D-(+)-Melezitose can be used to identify clinical isolates of indole-positive and indole-negative Klebsiella spp.

HY-N15015

Dephostatin	Natural Products Microorganisms Source Classification	Phosphatase
Dephostatin is a competitive protein tyrosine phosphatase (PTP) inhibitor that can be isolated from Streptomyces spp., with activity in the micromolar range .

HY-N12414

Apicularen A	Natural Products Microorganisms Source Classification	Bacterial
Apicularen A is a macrolide isolated from the mucoid bacterium Chondrosporium spp. Apicularen A is also a highly selective inhibitor of vesicular ATPase .

HY-N7709

Cinchonain IIb	Crataegus monogyna Jacq. Rosaceae Phenols Polyphenols Plants Source Classification	Others
Cinchonain IIb is a proanthocyanidin. Cinchonain IIb has the effect of rational utilization of decreased cardiac function. Cinchonain IIb is isolated from natural hawthorn (Crataegus spp. ) .

HY-N12882

(Z)-10-Hexadecen-1-ol	Natural Products Animals Source Classification	Others
(Z)-10-Hexadecen-1-ol is a insect sex pheromones, which can be secreted by some female nocturnal moths, or by the heads of male bumblebees (Bombus spp.) .

HY-N9075

9-(4′-Hydroxyphenyl)-2-methoxyphenalen-1-one	Monophenols Phenols Musaceae Plants Musa basjoo Sieb. et Zucc. Source Classification	Glycosidase
9-(4′-Hydroxyphenyl)-2-methoxyphenalen-1-one is a phytoalexin and mixed competitive α-glucosidase inhibitor of Bacillus stearothermophilus (IC₅₀: 3.86 mg/L) .

HY-N4108R

Hypophyllanthin (Standard)	Phyllanthus urinaria Linn. Lignans Euphorbiaceae Phenylpropanoids Plants Source Classification	Reference Standards P-glycoprotein
Hypophyllanthin (Standard) is the analytical standard of Hypophyllanthin. This product is intended for research and analytical applications. Hypophyllanthin is a major lignan in Phyllanthus spp, with strong anti-inflammatory activity. Hypophyllanthin directly inhibits P-glycoprotein (P-gp) activity and did not interfere with multidrug resistance protein 2 (MRP2) activity .

HY-12136R

Purpurogallin (Standard)	Structural Classification Phenols Polyphenols Plants Fagaceae Macaranga denticulata (Blume) Müll. Arg.	Xanthine Oxidase Reference Standards
Purpurogallin (Standard) is the analytical standard of Purpurogallin. This product is intended for research and analytical applications. Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC50 of 0.2 μM. Purpurogallin has antioxidant and anti-inflammatory effects .

HY-Y0760R

3-Methoxybenzoic acid (Standard) 3-Anisic acid (Standard); NSC 27014 (Standard); m-Methoxybenzoic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Drug Intermediate
3-Methoxybenzoic acid (3-Anisic acid; NSC 27014; m-Methoxybenzoic acid) (Standard) is the analytical standard of 3-Methoxybenzoic acid. This product is intended for research and analytical applications. 3-Methoxybenzoic acid is a substituted benzoic acid and precursor for synthesis of hydrazide-hydrazone derivatives active against Gram-positive bacteria, including Bacillus spp .

HY-N7071AR

Maduramicin ammonium (Standard) Maduramycin ammonium (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Reference Standards Bacterial Apoptosis Antibiotic
Maduramicin (ammonium) (Standard) is the analytical standard of Maduramicin (ammonium). This product is intended for research and analytical applications. Maduramicin ammonium (Maduramycin ammonium) is isolated from the actinomycete Actinomadura rubra. Maduramicin ammonium (Maduramycin ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection . Maduramicin ammonium (Maduramycin ammonium) induces cell apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways .

HY-W746884

2-Methyl-2-butenyl (E)-Caffeate	Structural Classification Animals Phenols Polyphenols Source Classification	Cholinesterase (ChE)
2-Methyl-2-butenyl (E)-Caffeate is a type of caffeic acid ester compound. The petroleum ether and chloroform extracts containing 2-Methyl-2-butenyl (E)-Caffeate have inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The ether extract containing 2-Methyl-2-butenyl (E)-Caffeate exhibits strong antioxidant properties. 2-Methyl-2-butenyl (E)-Caffeate can be used in the research of Alzheimer's disease .

HY-N7876

Ejaponine B	Structural Classification Terpenoids Sesquiterpenes Euonymus japonicus Thunb. Celastraceae Plants Source Classification	Drug Derivative
Ejaponine B is a natural product that can be found in Tripterygium wilfordii Hook. f., Begonia spp..

HY-N7941

Celangulin II	Structural Classification Terpenoids Sesquiterpenes Celastraceae Celastrus angulatus Maxim. Plants Source Classification	Drug Derivative
Celangulin II is a natural product that can be found in Tripterygium wilfordii Hook. f., Begonia spp..

HY-N7874

Celangulatin F	Structural Classification Terpenoids Sesquiterpenes Celastraceae Celastrus angulatus Maxim. Plants Source Classification	Drug Derivative
Celangulatin F is a natural product that can be found in Tripterygium wilfordii Hook. f., Begonia spp..

HY-N7873

Celangulin III	Structural Classification Terpenoids Celastraceae Diterpenoids Celastrus angulatus Maxim. Plants Source Classification	Drug Derivative
Celangulin III is a natural product that can be found in Tripterygium wilfordii Hook. f., Begonia spp..

HY-N2728

6-O-Syringoylajugol	Monophenols Phenols Pedaliaceae Plants Harpagophytum procumbens Source Classification	Others
6-O-Syringoylajugol (compound 65) is a natural product that can be found in Verbacum spp .

HY-125306

Rotihibin A	Natural Products Microorganisms Source Classification	Others
Rotihibin A is a novel plant growth regulator isolated from Streptomyces spp., which has the activity of inhibiting the growth of various plants without lethal activity.

HY-W142497

3-Methyl-2(5H)-furanone	Structural Classification Natural Products Nicotiana tabacum L. Solanaceae Plants Source Classification	Drug Intermediate
3-Methyl-2(5H)-furanone is the common structural unit in natural and several synthetic strigolactones, which are germination stimulants for seeds of the parasitic weeds Striga and Orobanche spp. .

HY-W017143

Antifungal agent 158	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Fungal
Antifungal agent 158 is an α-pyrone derivative that can be found in Trichoderma harzianum, exhibiting antifungal activity against select plant-pathogenic fungi, including Chaetomium spp., Curvularia lunata, and Aspergillus flavus. Antifungal agent 158 is non-toxic to greenhouse-grown bean, corn, and tobacco plants. Antifungal agent 158 can be used for research on Aspergillus flavus infection .

HY-N10625A

Cyprinol 5α-Cyprinol	Structural Classification Animals Steroids Source Classification	Phosphatase
Cyprinol (5α-Cyprinol) is an orally active bile salt and xenochemical pheromone . Cyprinol impairs renal function and increases plasma ALP activity in rats, induces diel vertical migration in Daphnia spp., enhances the permeability of the rectal mucosa to water-soluble compounds, and aids lipid digestion in fish. Cyprinol can be used in studies of fish toxicity and acute renal failure .

Cat. No.	Product Name	Chemical Structure

HY-N6740S

β-Zearalanol-d4
β-Zearalanol-d₄ is a deuterium labeled Beta-Zearalanol (HY-N6740） . Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .

HY-B2033S

Pyrimethanil-13C,15N2

Pyrimethanil- ¹³C, ¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Pyrimethanil. Pyrimethanil is an?anilinopyrimidine?and broad-spectrum?contact fungicide for the control of Botrytis spp. on a wide variety of crops . Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in?Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection .

HY-Y1636S

Fmoc-Arg(Pbf)-OH-13C6,15N4
Fmoc-Arg(Pbf)-OH- ¹³C₆, ¹⁵N₄ is the ¹³C-labeled and ¹⁵N-labeled Fmoc-Arg(Pbf)-OH (HY-Y1636). Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .

HY-131134S

Fosetyl-aluminum-d15
Fosetyl-aluminum-d₁₅ (Fosetyl-Al-d₁₅) is the deuterium labeled Fosetyl-aluminum. Fosetyl-aluminum (Fosetyl-Al) is an active ingredient in many fungicides against downy mildew. Fosetyl-aluminum is used to control many diseases caused by Phytophthora spp. on agricultural and horticultural crops .

HY-B0724BS

Pazufloxacin-d4

Pazufloxacin-d₄ is deuterium labeled Pazufloxacin (HY-B0724B). Pazufloxacin is an orally active fluoroquinolone antimicrobial agent. Pazufloxacin inhibits DNA gyrase with IC₅₀ values of 0.88 μg/mL (E. coli) and 1.9 μg/mL (P. aeruginosa). Pazufloxacin exhibits broad-spectrum antimicrobial activity, with MIC₉₀ values ranging from 0.025 to 100 μg/mL against Gram-positive and Gram-negative bacteria, non-fermenting bacteria, Legionella spp., and anaerobic bacteria. Pazufloxacin is indicated for research on systemic infections, lung infections, urinary tract infections, and Legionella pneumonia .

HY-W766785

Tiamulin Fumarate-13C4
Tiamulin Fumarate- ¹³C₄ is the ¹³C-labeled Tiamulin. Tiamulin (Thiamutilin) fumarate is a diterpenic antibiotic that is widely used in pigs and poultry for the control of infectious diseases. Tiamulin fumarate is effectively used in the study of airsacculitis, which is primarily caused by Mycoplasma spp .

HY-B2060S1

Tiamulin-d10-1 hydrochloride
Tiamulin-d₁₀-1 (hydrochloride) is deuterium labeled Tiamulin. Tiamulin (Thiamutilin) is a diterpenic antibiotic that is widely used in pigs and poultry for the control of infectious diseases. Tiamulin is effectively used in the study of airsacculitis, which is primarily caused by Mycoplasma spp .

HY-Y1636S1

Fmoc-Arg(Pbf)-OH-13C6
Fmoc-Arg(Pbf)-OH- ¹³C₆ is the ¹³C labeled Fmoc-Arg(Pbf)-OH . Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .

HY-N6740S2

Beta-Zearalanol-d5
Beta-Zearalanol-d₅ is the deuterium labeled Beta-Zearalanol (HY-N6740). Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of Zearalenone (HY-103447) which can conjugate with glucuronic acid .

HY-B2033S1

Pyrimethanil-d5

Pyrimethanil-d₅ is the deuterium labeled Pyrimethanil (HY-B2033). Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops . Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection .

HY-N7101S

Cefpodoxime proxetil-d7

Cefpodoxime proxetil-d7 (U-76-d7,252-d7; CS-807-d7) is the deuterium labeled Cefpodoxime Proxetil (HY-N7101). Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases .

HY-N6740S1

β-Zearalanol-13C18
β-Zearalanol- ¹³C₁₈ is the ¹³C-labeled β-Zearalanol. Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .

Cat. No.	Product Name		Classification

HY-151786

Fmoc-L-Lys(Pentynoyl-DIM)-OH		Alkynes Azide
Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151679

Fmoc-L-Lys(4-N3-Z)-OH		Azide
Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Lys(4-N3-Z)-OH acts as Lysine building-block for SPPS containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition . Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-136380

Clodinafop-propargyl		Alkynes
Clodinafop-propargyl, a main member of aryloxyphenoxy-propionate herbicides, is used for postemergence control of annual grasses in cereals, including Avena, Lolium, Setaria, Phalaris and Alopecurus spp . Clodinafop-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Clodinafop-propargyl has developmental toxicity to zebrafish embryos .

HY-151659

Fmoc-L-Lys(N3-Gly)-OH		Azide
Fmoc-L-Lys(N3-Gly)-OH is a click chemistry reagent containing a lysine-containing azidoacetyl group building-block for SPPS and can be used for various biochemical studies . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151671

Fmoc-L-MeLys(N3)-OH		Azide
Fmoc-L-MeLys(N3)-OH is a click chemistry reagent containing an azide. Fmoc-L-MeLys(N3)-OH is a SPPS building-block for the introduction of N-Me-Lys that can be modified at the N3-group using Click-chemistry . Fmoc-L-MeLys(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151787

Fmoc-L-Lys(N3-Aca-DIM)-OH		Azide
Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

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MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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SPPS

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

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