1 Result for "

TAS 303

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TAS 303" in MCE Product Catalog:

Cat. No.: HY-167227S
CAS No.: 1449371-87-2
Target:  

Monoamine Transporter

Research Areas:  

Neurological Disease

TAS-303 is an orally effective selective norepinephrine transporter (NET) inhibitor. TAS-303 inhibits human NET ligand binding with a Ki of 50.9 nM, and suppresses NET-mediated norepinephrine uptake with an IC50 of 38.9 nM. TAS-303 enhances norepinephrine-induced contraction in isolated rat urethral tissues, elevates plasma norepinephrine levels in rats, and increases urethral baseline pressure and leak point pressure. TAS-303 is applicable for research related to stress urinary incontinence, norepinephrine reuptake, and lower urinary tract function .

loading...
    loading...