1 Result for "

TNF-α-IN-29

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TNF-α-IN-29" in MCE Product Catalog:

Cat. No.: HY-182884
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

TNF-α-IN-29 is an orally active and selective TNF-α inhibitor, with IC50 values of 123.0 nM against human targets, and a human Kd of 45.9 nM. TNF-α-IN-29 blocks TNF-α-TNFR1 protein-protein interactions and inhibits TNF-α-mediated inflammatory signaling pathways. TNF-α-IN-29 exhibits anti-inflammatory effects in a mouse model of collagen-induced arthritis and promotes articular cartilage repair. TNF-α-IN-29 can be used for the research of rheumatoid arthritis .
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