1 Result for "

TX1-85-1 (Standard)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "TX1-85-1 (Standard)" in MCE Product Catalog:

Cat. No.: HY-100848R
CAS No.: 1603845-32-4
Research Areas:  

Cancer

TX1-85-1 (Standard) is the analytical standard of TX1-85-1 (HY-100848). This product is intended for research and analytical applications. TX1-85-1 is an irreversible Her3 (ErbB3) inhibitor with an IC50 of 23 nM. TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3. TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling .
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