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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
Ubiquitin-specific protease 7
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "Ubiquitin-specific protease 7" in MCE Product Catalog:
28
Target:
Research Areas:
P005091 is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with an EC50 of 4.2 μM.
24
24 Cited Publications
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Research Areas:
P 22077 is a cell-permeable ubiquitin-specific protease 7 (USP7) inhibitor with an EC50 of 8.01 μM. P 22077 also inhibits USP47 with an EC50 of 8.74 μM.
18
18 Cited Publications
Cat. No.: HY-17540
CAS No.: 1426944-49-1
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Research Areas:
HBX 19818 is a specific inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 28.1 μM.
6
6 Cited Publications
Cat. No.: HY-16709
CAS No.: 1381291-36-6
Target:
Research Areas:
USP7-IN-1 is a selective and reversible inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 77 μM, and can be used for the research of cancer.
4
4 Cited Publications
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Research Areas:
HBX 41108 is an inhibitor of ubiquitin-specific protease 7 (USP7) with an IC50 of 424 nM. HBX 41108 inhibits USP7-mediated p53 deubiquitination to stabilize p53 and inhibits cancer cell growth. BX 41108 can be used in cancer and diabetes research .
3
3 Cited Publications
Target:
Research Areas:
USP7/USP47 inhibitor is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM, respectively.
2
2 Cited Publications
Target:
Research Areas:
USP7-IN-3 (Compound 5) is an effective and selective allosteric inhibitor of ubiquitin-specific protease 7 (USP7). USP7-IN-3 can be used for research on acute lymphoblastic leukemia .
1
1 Cited Publications
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Research Areas:
USP7-IN-8 (example 81) is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM in an Ub-Rho110 assay. USP7-IN-8 shows no activity against USP47 and USP5. USP7-IN-8 has anticancer effects .
1
1 Cited Publications
Cat. No.: HY-P702603
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: USP7; HAUSP; Ubiquitin specific Peptidase 7; Ubiquitin-specific-Processing protease 7; Ubiquitin Carboxyl-Terminal Hydrolase 7; DeUbiquitinating Enzyme 7; Ubiquitin Thioesterase 7; Ubiquitin specific Peptidase 7 (Herpes Virus-Associated); Herpesvirus-Asso
Species:
Human
Source:
E. coli
Target:
Research Areas:
USP7-IN-11 is a potent ubiquitin-specific protease 7 (USP7) (Deubiquitinase) inhibitor with an IC50 of 0.37 nM. USP7-IN-11 has anticancer effects (WO2022048498A1; Example 187) .
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Research Areas:
USP7-IN-9 is a highly potent ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 value of 40.8 nM. USP7-IN-9 can induce apoptosis and arrest cell progression at G0/G1 and S phases in RS4; 11 cells. USP7-IN-9 reduces the protein levels of oncoproteins MDM2 and DNMT1 and increases the protein levels of tumor suppressors p53 and p21 .
Cat. No.: HY-148481
CAS No.: 2755995-01-6
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Research Areas:
USP7-IN-10 (compound 1) is a potent ubiquitin-specific protease 7 (USP7) inhibitor, with an IC50 of 13.39 nM .
Cat. No.: HY-148481A
Purity: 99.38%
Target:
Research Areas:
USP7-IN-10 hydrochloride (compound 1) is a potent ubiquitin-specific protease 7 (USP7) inhibitor, with an IC50 of 13.39 nM .
Cat. No.: HY-P85512
Synonyms: DeUbiquitinating enzyme 7; HAUSP; herpes virus associated; Herpes virus associated Ubiquitin specific protease; Herpesvirus-associated Ubiquitin-specific protease; TEF 1; tef-1; TEF1; Ubiquitin carboxyl terminal hydrolase 7; Ubiquitin carboxyl-terminal hydrolase 7; Ubiquitin specific peptidase 7; herpes virus associated; Ubiquitin specific peptidase 7; Ubiquitin specific peptidase 7 herpes virus associated; Ubiquitin specific processing protease 7; Ubiquitin specific protease 7; herpes virus associated; Ubiquitin specific protease 7; Ubiquitin specific protease 7 herpes virus associated; Ubiquitin thioesterase 7; Ubiquitin thiolesterase 7; Ubiquitin-specific-processing protease 7; UBP 7; UBP-7; UBP7; UBP7_HUMAN; USP 7; usp-7; USP7; VMW110-ASSOCIATED PROTEIN,135-KD.
Cat. No.: HY-P85431
Synonyms: USP7; HAUSP; Ubiquitin carboxyl-terminal hydrolase 7; DeUbiquitinating enzyme 7; Herpesvirus-associated Ubiquitin-specific protease; Ubiquitin thioesterase 7; Ubiquitin-specific-processing protease 7
Cat. No.: HY-129169
CAS No.: 2166586-47-4
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Research Areas:
USP7-IN-6 is a potent ubiquitin specific protease 7 (USP7) inhibitor, extracted from patent WO2017212010A1, example 25, has an IC50 of 6.8 nM .
Cat. No.: HY-P702604
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: USP7; HAUSP; Ubiquitin specific Peptidase 7; Ubiquitin-specific-Processing protease 7; Ubiquitin Carboxyl-Terminal Hydrolase 7; DeUbiquitinating Enzyme 7; Ubiquitin Thioesterase 7; Ubiquitin specific Peptidase 7 (Herpes Virus-Associated); Herpesvirus-Asso
Species:
Human
Source:
E. coli
Cat. No.: HY-P74478
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: USP7; HAUSP; Ubiquitin specific Peptidase 7; Ubiquitin-specific-Processing protease 7; Ubiquitin Carboxyl-Terminal Hydrolase 7; DeUbiquitinating Enzyme 7; Ubiquitin Thioesterase 7; Ubiquitin specific Peptidase 7 (Herpes Virus-Associated); Herpesvirus-Asso
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P704958
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: USP7; HAUSP; Ubiquitin specific Peptidase 7; Ubiquitin-specific-Processing protease 7; Ubiquitin Carboxyl-Terminal Hydrolase 7; DeUbiquitinating Enzyme 7; Ubiquitin Thioesterase 7; Ubiquitin specific Peptidase 7 (Herpes Virus-Associated); Herpesvirus-Asso
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-183689
CAS No.: 2947497-65-4
Target:
Research Areas:
OAT-4828 is an orally active ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 32 nM. OAT-4828 induces antileukemic activity in B-cell-derived non-Hodgkin's lymphoma models via inhibition of USP7. OAT-4828 is applicable to research related to chronic lymphocytic leukemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
