2763872-32-6
2763872-32-6
Chemical Structure
USP7-IN-11
- CAS 番号: 2763872-32-6
- Formula:C29H27ClN6O2S
- Molecular Weight:559.08
IUPAC Name: 4-((5-chloro-7-(2-((3-ethyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl)methyl)thieno[3,2-b]pyridin-7-yl)-1H-indol-1-yl)methyl)piperidine-4-carbonitrile
InChIKey: MYEHDMPQKCCTGD-UHFFFAOYSA-N
SMILES: CCN(C=CC1=O)C(N1CC2=CC3=NC=CC(C4=CC(Cl)=CC5=C4N(CC6(C#N)CCNCC6)C=C5)=C3S2)=O
Biological Activity: USP7-IN-11 is a potent ubiquitin-specific protease 7 (USP7) (Deubiquitinase) inhibitor with an IC50 of 0.37 nM. USP7-IN-11 has anticancer effects (WO2022048498A1; Example 187)[1].
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USP7-IN-11 | 99.19% | USP7-IN-11 is a potent ubiquitin-specific protease 7 (USP7) (Deubiquitinase) inhibitor with an IC50 of 0.37 nM. USP7-IN-11 has anticancer effects (WO2022048498A1; Example 187). | ||||||||||||||||||||
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