1. Cell Cycle/DNA Damage
  2. Deubiquitinase
  3. USP7-IN-6

USP7-IN-6 

Cat. No.: HY-129169
Handling Instructions

USP7-IN-6 is a potent ubiquitin specific protease 7 (USP7) inhibitor, extracted from patent WO2017212010A1, example 25, has an IC50 of 6.8 nM.

For research use only. We do not sell to patients.

USP7-IN-6 Chemical Structure

USP7-IN-6 Chemical Structure

CAS No. : 2166586-47-4

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Description

USP7-IN-6 is a potent ubiquitin specific protease 7 (USP7) inhibitor, extracted from patent WO2017212010A1, example 25, has an IC50 of 6.8 nM[1].

IC50 & Target

IC50: 6.8 nM (USP7)[1]

In Vitro

USP7-IN-6 (example 25) shows cytotoxicity to Z138 tumour cells, with an IC50 1.1 nM[1].

Molecular Weight

729.89

Formula

C₄₁H₄₃N₇O₄S

CAS No.

2166586-47-4

SMILES

O=C1C2=C(N(C3=CC=C(CO)C=C3)C=C2)N=CN1CC4(O)CCN(C([[email protected]]5[[email protected]](C6=CC=CC=C6)CN(CC7=CN=C(C8=CC=C(C)N=C8)S7)CC5)=O)CC4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

USP7-IN-6DeubiquitinaseDUBscytotoxicitycellstumorZ138Inhibitorinhibitorinhibit

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USP7-IN-6
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