1 Result for "

VEGFR-2-IN-77

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VEGFR-2-IN-77" in MCE Product Catalog:

Cat. No.: HY-179032
CAS No.: 169205-26-9
Target:  

VEGFR PI3K Akt mTOR Apoptosis

Research Areas:  

Cancer

VEGFR-2-IN-77 (Compound 10) is a VEGFR-2 inhibitor with an IC50 value of 139 nM. VEGFR-2-IN-77 inhibits the PI3K/AKT/mTOR pathway. VEGFR-2-IN-77 exhibits selective cytotoxicity, being particularly sensitive to leukemia and prostate cancer cells. VEGFR-2-IN-77 causes cell cycle arrest and apoptosis, inhibiting cell migration and invasion. VEGFR-2-IN-77 can be used for the study of leukemia and prostate cancer.
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